Interferon alpha-2b human recombinant has immunomodulatory, antiviral and antiproliferative properties. It suppresses replication of RNA- and DNA-containing viruses. Immunomodulatory properties of interferon such as increased phagocytic activity of macrophages, increased specific cytotoxicity of lymphocytes to target cells determine its mediated antibacterial activity.
In the presence of antioxidants alpha-tocopherol acetate, citric and benzoic acids increases specific antiviral activity of interferon and its immunomodulatory effect, which increases the effectiveness of the body’s own immune response to infectious agents.
The preparation has a pronounced local immunomodulatory effect and promotes increase of locally produced antibodies of class secretory IgA which prevent fixation and reproduction of pathogenic microorganisms on mucous membranes and this provides prophylactic effect of the preparation for prevention of viral and other diseases.
The gel base provides prolonged action of the drug. The antioxidants contained in the dosage form – alpha-tocopherol acetate, citric and benzoic acids possess anti-inflammatory, membranostabilizing and regenerating properties, and also help to save the biological activity of human recombinant interferon alpha-2b.
Indications
in the complex therapy of acute respiratory viral infections, including influenza, frequent and prolonged acute respiratory viral infections, including those complicated by bacterial infection;
prevention of acute respiratory viral infections, including influenza;
in complex therapy of recurrent stenotic laryngotracheobronchitis;
prevention of recurrent stenosing laryngotracheobronchitis;
in complex therapy of acute and exacerbations of chronic recurrent herpetic infections of the skin and mucous membranes, including the urogenital form of herpetic infection;
in complex therapy of herpetic cervicitis.
Pharmacological effect
Pharmacotherapeutic group
Cytokine.
ATX code
L03АВ05
Pharmacological properties
Human recombinant interferon alpha-2b has immunomodulatory, antiviral and antiproliferative properties. Suppresses the replication of RNA and DNA viruses. The immunomodulatory properties of interferon, such as increased phagocytic activity of macrophages and increased specific cytotoxicity of lymphocytes to target cells, determine its indirect antibacterial activity.
In the presence of antioxidants alpha-tocopherol acetate, citric and benzoic acids, the specific antiviral activity of interferon increases, its immunomodulatory effect increases, which makes it possible to increase the effectiveness of the body’s own immune response to infectious agents.
The drug has a pronounced local immunomodulatory effect and helps to increase locally formed antibodies of the secretory IgA class, which prevent the fixation and proliferation of pathogenic microorganisms on the mucous membranes, which provides a prophylactic effect of the drug for the prevention of viral and other diseases.
The gel base ensures a prolonged effect of the drug. The antioxidants included in the dosage form – alpha-tocopherol acetate, citric and benzoic acids – have anti-inflammatory, membrane-stabilizing, regenerating properties, and also help preserve the biological activity of human recombinant interferon alpha-2b.
Special instructions
Impact on the ability to drive vehicles and engage in other activities
Not installed.
Active ingredient
Interferon alpha-2b
Composition
1 g of gel for external and local use contains the active substance: human recombinant interferon alpha-2b 36,000 IU;
excipients: alpha-tocopherol acetate 0.055 g, methionine 0.0012 g, benzoic acid 0.00128 g, citric acid monohydrate 0.001 g, sodium tetraborate decahydrate 0.0018 g, sodium chloride 0.004 g, human albumin 0.002 g, distilled glycerin (glycerol) 0.02 g, carmellose sodium 0.02 g, ethanol 95% 0.055 g, purified water to 1 g.
Pregnancy
Pregnancy and breastfeeding are not a contraindication for the use of the drug due to the very low absorption of the components. During breastfeeding, do not apply to the area of the nipples and areola.
Contraindications
Hypersensitivity to any of the components of the drug.
Side Effects
In rare cases, allergic reactions (skin rashes, itching) may develop.
Interaction
Not detected.
Overdose
Not installed.
Storage conditions
At temperatures from 2 to 8 C.
Keep out of the reach of children.
Shelf life
1 year
Do not use the drug after the expiration date.
Manufacturer
Feron, Russia
Shelf life | 1 year |
---|---|
Conditions of storage | In a dry, light-protected place at 2-8 °C |
Manufacturer | Feron, Russia |
Medication form | gel for external use |
Brand | Feron |
Other forms…
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