Venoplant, 20 pcs.
€16.88 €14.06
Pharmacotherapeutic group
Venotonizing agent of plant origin.
TACH Codes
C05CX
Pharmacological properties
. Reduces capillary permeability, has venotonic, anti-edema, anti-inflammatory and angioprotective effect.
Prevents the activation of lysosomal enzymes that break down proteoglycan, increases the tone of the venous wall, eliminates venous congestion, decreases capillary permeability and
fragility. Reduces exudation, reduces fluid effusion into the tissues and accelerates the resorption of existing edema. Inhibits inflammation, improves microcirculation, promotes repair of organs and tissues.
Pharmacokinetics
Horse chestnut seed extract dry contains a large number of biologically active substances that together determine its pharmacological activity. Therefore the data on the pharmacokinetics of individual chemical components included in the extract are not sufficient for extrapolation to the drug as a whole.< br>
Indications
Swelling, Varicose Veins, Weight and pain in the legs
Chronic venous insufficiency class I – III according to CEAP classification: varicose veins, swelling, cramps in the calf muscles, heavy legs.
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Active ingredient
Horse chestnut seed extract.
Composition
(per tablet):
Active ingredient:
Horse chestnut ⃰ seed extract dry (4.5 – 5.5:1) ** – 263.2 mg, standardized by the sum of triterpene glycosides in terms of escine anhydrous*** – 50 mg,
Auxiliary components of the core:
calcium hydrophosphate anhydrous – 36,800 mg, colloidal silicon dioxide – 15,400 mg, Eudragit RL 30 D/dry substance (Aqueous suspension: (copolymer of poly(ethylacrylate : methylacrylate : trimethylammonioethyl methacrylate chloride) 1:2:0.2 30.0 g ; sorbic acid 0.25 g ; purified water to 100.0 ml) – 14.000 mg, Eudragit RS 30 D/dry substance (Aqueous suspension: (copolymer poly(ethylacrylate : methylacrylate : trimethylammonioethyl methacrylate chloride) 1:2:0.1 30.0 g; sorbic acid 0.25 g ; purified water to 100.0 ml) – 10.000 mg, triethylcitrate – 3.564 mg, polysorbate 80 – 0.036 mg, povidone K 25 – 20.000 mg, crosspovidone – 10.000 mg, magnesium stearate 2.000 mg,
Components of the shell:
hypromellose (5 mPa ∙ c) – 11.660 mg, macrogol 4000 – 2.910 mg, iron oxide red (E172) – 0.220 mg, iron oxide yellow (E172) – 1.090 mg, titanium dioxide (E171) – 0.680 mg, defoaming emulsion/dry substance (dimethicone 18.5 %; Colloidal anhydrous silica 1,5% ; α-octadecyl ω-hydroxypoly(oxyethylene)-5 -3,0% ; Sorbic acid 0,1% ; purified water 76,9%) – 0,010 mg, talc – 1,000 mg, sodium saccharinate – 0,025 mg, vanillin – 0,405 mg.
* dry extract obtained from the seeds of Aesculus hippocastanum L, family. Hippocastanaceae
** extractant: ethanol 50%
*** extract standardized with an adjuvant:
horse chestnut* seed extract dry** (4.5 – 5.5:1) – 178,500 – 263,200 mg;
calcium hydrophosphate anhydrous 0,000 – 84,700 mg
How to take, the dosage
Orally, 1 tablet two times a day (morning and evening) without chewing, with plenty of fluid, before a meal.
Treatment duration is determined by the doctor depending on the severity of symptoms and is no more than 16 weeks.
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Interaction
Concomitant use with indirect anticoagulants is not recommended because Venoplant enhances their action.
Special Instructions
It is necessary to strictly follow all additional prescriptions of the doctor, such as bandaging the legs, wearing elastic stockings, cold foot baths.
If you have a history of thrombophlebitis, cardiac or renal insufficiency, you should consult your doctor.
If symptoms are suddenly strongly pronounced (especially on one leg), such as severe swelling, skin discoloration, a feeling of tension, heat, pain, you should immediately consult a physician, as they may be symptoms of a serious illness – lower limb venous thrombosis.
If the symptoms persist or worsen during 6 weeks after the use of the drug, inform the attending physician.
Impact on ability to drive vehicles, mechanisms
During the period of the drug use one should be careful while performing potentially dangerous activities that require high concentration and quick psychomotor reactions (driving vehicles, operating moving mechanisms, operator’s work).
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Synopsis
Round biconvex light brown tablets, the fracture shows a light brown coating and a brown to light brown core.
Contraindications
Hypersensitivity to horse chestnut seed extract or any of the ingredients. Childhood (under 18 years of age).
Side effects
Allergic reactions (fever, urticaria, skin rash, itching, anaphylactic shock), dyspepsia (including nausea), dizziness, headache.
If you observe any undesirable effects while using the drug, please inform your attending physician.
Overdose
Cases of overdose of the drug have not yet been registered.
In case of overdose you should consult a physician.
Pregnancy use
Due to the lack of sufficient clinical data, it is not recommended to use the drug during pregnancy and breastfeeding.
Weight | 0.020 kg |
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Shelf life | 3 years. Do not use after the expiration date! |
Conditions of storage | Store at a temperature not exceeding 25 ° C |
Manufacturer | Dr. Willmar Schwabe GmbH & Co. KG, Germany |
Medication form | slow-release tablets |
Brand | Dr. Willmar Schwabe GmbH & Co. KG |
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