Valoserdin, drops, 15 ml

Valoserdin is a combination drug. Phenobarbital has sedative and mild sleeping pills.

It helps to reduce CNS agitation and facilitates the onset of natural sleep.

Ethylbromisovalerianate also has sedative and antispasmodic effects.

Pearmint oil has reflex vasodilator and antispasmodic activity.

Indications

Cramps, Anxiety, Insomnia, Irritability, Cardialgia (heart pain), Hypertension (high blood pressure), Heart pain, Neurosis, Sleep disturbance

• vegetovascular dystonia
• high irritability
• insomnia
• arterial hypertension (early stages).

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Active ingredient

Peppermint Leaf Oil, Phenobarbital, Hops Straw Oil, Ethyl Bromisovalerianate

Composition

100 g drops for oral administration contain:

acting substances:

phenobarbital 2 g,

ethyl bromisovalerianate (ethyl ester of α-bromisovaleric acid) 2 g,

excipients:

Pearmint oil – 0.14 g;

Spanish hop oil (oregano oil) – 0.02 g;

Ethanol (ethyl alcohol) 95% – 52.8 g;

Purified water – 43.04 g.

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How to take, the dosage

Overly, before meals, dissolved in a small amount (30-50 ml) of water. Adults are usually prescribed 15-20 drops 3 times a day. In case of tachycardia the single dose may be increased up to 40-50 drops.

The duration of the drug shall be determined by the physician individually.

Interaction

Simultaneous use with neuroleptics and tranquilizers increases the effects of each component of the drug, and with CNS stimulants it weakens them.

Alcohol increases the effects of Valoserdin and may increase its toxicity.

The presence of phenobarbital in the composition may induce liver enzymes, and this makes it undesirable to use it simultaneously with drugs that are metabolized in the liver, because their concentration, and therefore their effectiveness will be reduced due to more rapid metabolism (indirect anticoagulants, antibiotics, sulfonamides).

Phenobarbital attenuates the effects of coumarin derivatives, GCS, griseofulvin, oral contraceptives.

Special Instructions

Consultation with a physician is necessary before starting to use the drug.

If it is necessary to prescribe the drug while breastfeeding, the question of stopping breastfeeding should be decided.

Long-term use of the drug may lead to drug addiction; bromine may accumulate in the body and lead to bromine poisoning.

The drug contains at least 52 vol.% of ethanol.

The maximum single dose of the drug contains 1.03 g of absolute ethanol; the maximum daily dose is 3.09 g of absolute ethanol.

Impact on the ability to drive vehicles, machinery. While using the drug it is not recommended to perform potentially hazardous activities, requiring high concentration and quick psychomotor reactions (including driving vehicles and operating moving mechanisms).

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Contraindications

• high sensitivity to the components of the drug
• explicit renal and/or hepatic impairment;
• porphyria;
• pregnancy;
• breastfeeding period;
• age below 18 years.

Because of the content of absolute ethyl alcohol more than 3 g in a daily dose Valoserdin is contraindicated in patients with liver diseases, alcoholism, craniocerebral trauma and brain diseases.

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Side effects

Valoserdin is generally well tolerated, even with long-term use. Drowsiness and mild dizziness may be observed in some cases during daytime hours. With long-term use of high doses it is possible to develop chronic bromine poisoning characterized by the following manifestations: depressed mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements.

If you have any side effects (unusual) that are not listed, you should tell your doctor.

Overdose

Symptoms: in mild and moderate intoxication drowsiness, dizziness, psychomotor disorders are observed. In severe cases – coma, BP decrease, respiratory disorders, tachycardia, vascular collapse, decreased peripheral reflexes.

Treatment: gastric lavage, administration of activated charcoal. A physician should be called.

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Similarities

Valokordin, Valokordin-Doxylamine