Triderm, cream 15 g
€25.45 €22.05
Pharmacological group:
Glucocorticosteroid+antibiotic-aminoglycoside+antifungal agent.
Pharmacological action:
Triderm is a combination drug,.
The Triderm® ointment and cream combines the anti-inflammatory, anti-pruritic, anti-allergic and anti-exudative effects of betamethasone dipropionate with the antifungal activity of clotrimazole and the broad antibacterial action of gentamicin sulfate.
Clotrimazole has antifungal action (inhibits the synthesis of the cell membrane ergosterol of fungi). It is active against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furfur (Pityrosporum orbiculare).
Gentamicin sulfate, a broad-spectrum antibiotic of the aminoglycoside group, acts bactericidally and provides highly effective local treatment of primary and secondary bacterial skin infections. It is active against Gram-negative microorganisms: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; Gram-positive microorganisms: Streptococcus spp. (sensitive strains of alpha- and beta-hemolytic Streptococcus group A), Staphylococcus aureus (coagulase-positive, coagulase-negative and some strains producing penicillinase).
Indications
Reduction of inflammatory manifestations of dermatoses complicated by primary and secondary infection (simple and allergic dermatitis, atopic dermatitis, diffuse neurodermitis, limited neurodermitis);
epidermophytia of the feet;
pityriasis;
Active ingredient
Composition
1 g cream contains:
betamethasone 0.5 mg,
clotrimazole 10 mg,
gentamicin 1 mg.
Associates:
liquid paraffin,
white I Vaseline,
cetostearyl alcohol,
propylene glycol,
cetomacrogol-1000.
Petrol alcohol,
J sodium bicarbonate phosphate dihydrate,
phosphoric acid,
sodium hydroxide (to set the required pH value),
purified water (q.s. ad 1000 mg).
How to take, the dosage
The cream is used in the treatment of acute wet skin lesions – in processes with blotchy and pronounced inflammation.
Triderm Cream should be applied in a thin layer over the entire affected skin surface and the surrounding tissue twice a day in the morning and at night. For the treatment to be effective it is necessary to use TRIDERM cream regularly.
The duration of therapy depends on the size and location of the lesion as well as the patient’s reaction. If there is no clinical improvement after 3-4 weeks of treatment this may indicate a diagnosis.
Special Instructions
It should not be used in ophthalmic practice.
Long-term topical use of antibiotics can sometimes lead to the growth of resistant microflora. In this case, as well as if irritation, sensitization or superinfection develops while using Triderm, treatment should be stopped and appropriate therapy should be prescribed. Cross-allergic reactions with aminoglycoside antibiotics have been observed.
Any side effects common with systemic glucocorticosteroids, including inhibition of adrenal function, may also be seen with topical glucocorticosteroids, particularly in children. Systemic absorption of glucocorticosteroids or gentamicin when applied topically will be higher if treatment is given over a larger body surface or if occlusive dressings are used.
Application of gentamicin to open wounds or skin injuries should be avoided. Appropriate precautions should be taken in such cases, especially when treating children.
The withdrawal of the drug after long-term use is recommended to be done gradually.
Pediatric use: In children from 2 years of age, only if strictly indicated and under medical supervision, because of possible systemic side effects associated with betamethasone. When using Triderm, as well as many other topical glucocorticosteroids on large surfaces and/or with an occlusive dressing, suppression of hypothalamic-pituitary-adrenal system function may occur, decreased growth hormone excretion and increased intracranial pressure may be observed.
Contraindications
Hypersensitivity to any of the ingredients of Triderm;
Tuberculosis of the skin;
Cutaneous manifestations of syphilis;
chicken pox;
herpes simplex;
cutaneous postvaccination reactions;
under 2 years of age.
Side effects
Topical reactions:burning sensation, erythema, exudation, pigmentation disorders, itching.
Betamethasone-related adverse reactions:Burning sensation, itching, skin irritation and dryness, folliculitis, hypertrichosis, acne rashes, hypopigmentation, perioral dermatitis, skin maceration, secondary infection, skin atrophy, stretch marks, sweat.
Corrective reactions due to clotrimazole: erythema, scaling, local edema, itching, urticaria, skin maceration, paresthesias.
Gentamicin-related adverse reactions: hyperemia, itching.
Overdose
Long-term use of glucocorticosteroids in high doses may cause symptoms of hypercorticism.
The use of clotrimazole under an occlusive dressing for 6 hours has not led to the development of symptoms of overdose.
Pregnancy use
The use of TRIDERM during pregnancy is possible only when the expected benefits to the mother outweigh the potential risk to the fetus.
It is not known whether the components of the drug are excreted in the breast milk.
Therefore, if TRIDERM is prescribed during lactation, discontinuation of breastfeeding should be considered.
Similarities
Weight | 0.026 kg |
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Shelf life | 3 years. |
Conditions of storage | Store at a temperature of +2 ° C to +30 ° C. |
Manufacturer | Bayer Bitterfeld GmbH, Germany |
Medication form | exterior cream |
Brand | Bayer Bitterfeld GmbH |
Other forms…
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