Tobrex, eye drops 0.3% 5 ml

Tobrex eye drops contain tobramycin, a broad-spectrum antibiotic of the aminoglycoside group. Bactericidal effect of the drug extends to Streptococcus and Staphylococcus bacteria, Klebsiella, Escherichia coli, diphtheria bacteria.

In low concentrations the action is bacteriostatic (blocks 30S ribosome subunit and disturbs protein synthesis) and in higher concentrations it is bactericidal (disturbs cytoplasmic membrane function, causing death of microbial cell).

Highly active against Staphylococcus spp. (including Staphylococcus aureus, Staphylococcus epidermidis /coagulase-negative and coagulase-positive/ and penicillin-resistant strains); Streptococcus spp.including α-β-haemolytic species, some non-haemolytic species, Streptococcus pneumoniae); Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis (indole-negative) and indole-positive species of Proteus spp, Haemophilus influenzae, Haemophilus aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus (Herellea vaginacola), some Neisseria spp. species (including Neisseria gonorrhoeae).

Pharmacokinetics

In local administration systemic absorption is low.

Indications

Eye Infections, Eye Redness, Blepharitis, Iridocyclitis, Conjunctivitis, Inflammatory Eye DiseasesInfections of the eye and its appendages:
– blepharitis;
– conjunctivitis;
– keratoconjunctivitis;
– blepharoconjunctivitis;
– keratitis;
– iridocyclitis.
Prevention of postoperative infections.

Active ingredient

Tobramycin

How to take, the dosage

Locally.

Interaction

In case of concomitant administration of tobramycin topically with systemic aminoglycoside antibiotics, there may be increased side effects of systemic nature.

Special Instructions

Contact lenses should not be worn during treatment with the drug.

Long-term use of Tobrex eye drops, as with other antibiotics, may lead to increased growth of non-susceptible microorganisms (including fungi). It is recommended that cultures be taken before and after treatment if the clinical result is unsatisfactory.

Impact on driving and operating machinery

It is not recommended to drive or operate complex machinery, machines, or any other complex equipment that requires visual clarity in patients who have temporarily impaired visual clarity after Tobrex instillation.

Contraindications

Hypersensitivity to the components of the drug.

Side effects

Local. Allergic reaction accompanied by itching and swelling of the eyelids, conjunctival hyperemia, lacrimation.

Overdose

Symptoms: pitting keratitis, erythema, increased lacrimation, itching, and eyelid edema.

Pregnancy use

There is no sufficient experience in using the drug during pregnancy and lactation (breastfeeding). It is possible to use Tobrex eye drops in pregnant women and nursing mothers when the expected therapeutic effect exceeds the potential risk of side effects.

Performance in children

There is no sufficient experience in the use of Tobrex eye drops in children. The drug may be used in children if the expected therapeutic effect exceeds the potential risk of side effects.

Similarities

Tobropt, Tobriss eye drops