Telprez Plus, tablets 80 mg+12, 5 mg 28 pcs

Hypotensive combined agent (angiotensin II receptor antagonist + diuretic) Telpres Plus is a combination of telmisartan (angiotensin II receptor antagonist) and hydrochlorothiazide – thiazide diuretic.

Indications

Hypertension (high blood pressure)Arterial hypertension (if telmisartan or hydrochlorothiazide is ineffective in monotherapy)

Active ingredient

Hydrochlorothiazide, Telmisartan

Composition

1 tablet hydrochlorothiazide 12.5 mg

How to take, the dosage

Orally, regardless of the time of meals.

Telprez Plus must be taken once a day.

• Telprez Plus 12.5/40 mg may be indicated in patients in whom the use of telmisartan 40 mg or hydrochlorothiazide does not adequately control BP.
• Telprez Plus 12.5/80 mg may be indicated in patients in whom the use of telmisartan 80 mg or Telprez Plus 12.5/40 mg does not adequately control BP.
• Telprez Plus 25/80 mg may be indicated in patients in whom the use of telmisartan 80 mg or Telprez Plus 12.5/80 mg does not adequately control BP, or in patients whose condition has previously been stabilized by telmisartan or hydrochlorothiazide when used separately.

In patients with severe arterial hypertension, the maximum daily dose of telmisartan is 160 mg in combination with hydrochlorothiazide at a daily dose of 12.5-25 mg.

Renal dysfunction

Limited experience with Telprez Plus in patients with mild to moderate renal dysfunction does not require a change in the dose of the drug in these cases. Renal function should be monitored in such patients (if CK is less than 30 ml/min, see section “Contraindications”).

Hepatic disorders

In patients with mild to moderate hepatic impairment (Child-Pugh Class A and B), the daily dose of Telpras Plus should not exceed 12.5/40 mg daily (see “Pharmacokinetics” section).

Elderly patients

The dosing regimen requires no changes.

Directions for use

Orally, regardless of the time of meals. The drug Telprez Plus should be taken once a day. Telprez Plus 12.5/40 mg may be administered to patients in whom the use of telmisartan 40 mg or hydrochlorothiazide does not adequately control BP.

Contraindications

Hypersensitivity to the active substances or excipients of the drug or other sulfonamide derivatives;

Side effects

1) expected based on experience with telmisartan 2) expected based on experience with hydrochlorothiazide 3) side effects not observed in clinical trials with telmisartan and hydrochlorothiazide concomitantly, but expected during administration of Telprez Plus

Overdose

Information regarding overdose is limited. Possible symptoms of overdose consist of the symptoms of the individual components of the drug.

Similarities

Mycardis Plus, Telsartan N, Telzap Plus, Telpres Plus, Telmista N, Mikafor