Sulfadimethoxin, tablets 500 mg, 10 pcs.

An antibacterial agent derived from sulfonamide. It has a long-lasting effect when administered orally. Mechanism of action is related to competitive antagonism with PABA and competitive inhibition of dihydropteroatsintase, which leads to disruption of tetrahydrofolic acid synthesis required for synthesis of purines and pyrimidines.

Active against Gram-positive bacteria: Staphylococcus spp., Streptococcus spp. (including Streptococcus pneumoniae); Gram-negative bacteria: Klebsiella pneumoniae, Escherichia coli, Shigella spp.

Active against Chlamydia trachomatis.

Indications

Infectious and inflammatory diseases caused by sensitive microflora: tonsillitis, sinusitis, otitis media, dysentery, inflammatory diseases of the biliary and urinary tract (uncomplicated), erysipelas, wound infection, trachoma.

Pharmacological effect

Antibacterial agent, sulfanilamide derivative. Has a long-lasting effect when taken orally. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidines.

Active against gram-positive bacteria: Staphylococcus spp., Streptococcus spp. (including Streptococcus pneumoniae); gram-negative bacteria: Klebsiella pneumoniae, Escherichia coli, Shigella spp.

Active against Chlamydia trachomatis.

Special instructions

During treatment, it is recommended to drink plenty of alkaline fluids and monitor blood and urine counts.

It is used externally as part of combination preparations.

Active ingredient

Sulfadimethoxine

Composition

Active ingredient:

sulfadimethoxine 200 mg.

Contraindications

severe renal dysfunction
diseases of the hematopoietic system
hypersensitivity to the drug.

Side Effects

From the side of the central nervous system: possible headache.

From the digestive system: dyspeptic symptoms, nausea, vomiting, cholestatic hepatitis.

Allergic reactions: skin rashes, drug fever.

From the hematopoietic system: rarely – leukopenia, agranulocytosis.

Interaction

Sulfadimethoxine reduces the effectiveness of bactericidal antibiotics that act only on dividing microorganisms (including penicillins, cephalosporins).

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C

Shelf life

5 years

Manufacturer

Biosynthesis, Russia