Sulfadimethoxin, tablets 500 mg, 10 pcs.

An antibacterial agent derived from sulfonamide. It has a long-lasting effect when administered orally. Mechanism of action is related to competitive antagonism with PABA and competitive inhibition of dihydropteroatsintase, which leads to disruption of tetrahydrofolic acid synthesis required for synthesis of purines and pyrimidines.

Active against Gram-positive bacteria: Staphylococcus spp., Streptococcus spp. (including Streptococcus pneumoniae); Gram-negative bacteria: Klebsiella pneumoniae, Escherichia coli, Shigella spp.

Active against Chlamydia trachomatis.

Indications

Infectious inflammatory diseases caused by susceptible microflora: tonsillitis, maxillitis, otitis media, dysentery, biliary and urinary tract inflammatory diseases (uncomplicated), rye, wound infection, trachoma.

Active ingredient

Composition

The active ingredient:

sulfadimethoxin 200 mg.

How to take, the dosage

Sulfadimethoxin is taken orally.

Take every 24 hours: 1-2 g on day 1, 0.5-1 g/day on subsequent days; children 25 mg/kg/day on day 1 and 12.5 mg/kg/day on subsequent days.

Interaction

Sulfadimethoxin reduces the effectiveness of bactericidal antibiotics acting only on fissile microorganisms (including penicillins, cephalosporins).

Special Instructions

During treatment it is recommended to drink plenty of alkaline fluids, monitor blood and urine parameters.

It is used externally as part of the combination therapy.

Contraindications

Side effects

CNS disorders: headache possible.

Digestive system disorders: dyspeptic symptoms, nausea, vomiting, cholestatic hepatitis.

Allergic reactions: skin rashes, drug fever.

Hematopoietic system: rarely – leukopenia, agranulocytosis.