Streptococcus bacteriophage, 20 ml 4 pcs

Streptococcus bacteriophage is an immunobiological drug, phage.

Streptococcal bacteriophage has the ability to specifically lyse streptococcal bacteria (streptococci, enterococci) isolated in purulent infections.

Indications

Active ingredient

Composition

The drug is a sterile phagolysate filtrate active against streptococcal bacteria most important in the etiology of pyo-inflammatory diseases.

How to take, the dosage

An important condition for effective phagotherapy is prior determination of phage sensitivity of the pathogen (isolation of Streptococcus strains susceptible to Streptococcus bacteriophage from patients).

Condition for the successful use of streptococcal bacteriophage is early use of the drug and the possibility of direct introduction into the focus of infection. The course of treatment is 5-15 days. In the recurrent course of the disease it is possible to conduct repeated courses of treatment.
Depending on the nature of the focus of infection Streptococcus bacteriophage is used: locally in the form of irrigation, lotions and swabs; in pleural, joint and other limited cavities; in the bladder through a catheter; per os and per rectum.)

Topically in the form of irrigation, lotions and tamponization with liquid phage in an amount up to 200 ml, depending on the size of the affected area.
Treatment of purulent inflammatory diseases with localized lesions is advisable to be carried out simultaneously both topically and by mouth for 7-20 days.

In purulent inflammatory diseases of ear, throat, nose streptococcal bacteriophage is administered in dose 2-10 ml 1-3 times a day; it is used for gargling, irrigation, dipping, introduction of soaked turundae (leaving them in for 1 hour).

In boils and carbuncles streptococcal bacteriophage may be injected directly into the focus or under the base of infiltrate as well as around the focus by injection. Injections are made daily or every other day depending on the reaction in sequentially increasing doses: 1 injection – 0.5 ml, then 1.0 – 1.5 – 2.0 ml. A total of 3-5 injections per treatment cycle.

In case of abscesses streptococcal bacteriophage is injected into the nidus cavity after removal of pus by punctures. The amount injected should be slightly less than the volume of the removed pus. Pus may be removed by opening the abscess, followed by insertion of a swab abundantly moistened with Streptococcus bacteriophage into the cavity.

In case of osteomyelitis after appropriate surgical treatment streptococcal bacteriophage is injected into the wound (10-20 ml).
Introduction of up to 100 ml of streptococcal bacteriophage into pleural, articular and other confined cavities, after which capillary drainage is left, through which and within a few days the bacteriophage is re-injected.

In cystitis streptococcal bacteriophage is injected into the bladder through a catheter.

In purulent pleurisy, bursitis or arthritis, streptococcal bacteriophage is injected into the cavity (after removal of pus) in an amount of 20 ml or more, every other day, 3-4 times in total.

In purulent inflammatory gynecological diseases streptococcal bacteriophage is injected into the cavity of the vagina, uterus in a dose of 5-10 ml once daily.

In cystitis, pyelonephritis, urethritis streptococcal bacteriophage is taken orally. If the bladder cavity or renal pelvis are drained, bacteriophage is injected through cystostoma or nephrostoma 20-50 ml into the bladder and 5-7 ml into renal pelvis 1-2 times a day.

In intestinal forms of the disease caused by streptococcal bacteria and intestinal dysbacteriosis liquid streptococcal bacteriophage is used orally and rectally by enema. Orally taken 3 times a day on an empty stomach 1-1.5 hours before a meal. Rectally in the form of enemas are administered once a day instead of one dose by mouth. In case of dysbacteriosis and internal diseases the treatment is carried out for 7-10 days under bacteriological control.

In children of the first two days of life in the first two days of administration Streptococcus bacteriophage should be diluted with boiled water by a factor of 2. If there are no adverse reactions (regurgitation, skin rashes) the drug should be used undiluted thereafter. In this case it is mixed with breast milk.

In case of sepsis, enterocolitis of newborns, including premature infants, Streptococcus bacteriophage is used in the form of high enemas (through a gas tube or catheter) 2-3 times a day. A combination of rectal (in enemas) and oral (by mouth) administration of the drug is possible.

In the treatment of omphalitis, pyodermia, infected wounds in newborns Streptococcus bacteriophage is used in the form of applications twice a day (a gauze napkin is wetted with bacteriophage and put on the umbilical wound or on the affected skin area).
Recommended dosage of Streptococcus bacteriophage:

Streptococcus bacteriophage is used for prophylaxis in an amount up to 50 ml for irrigation of a postoperative wound, vaginal or uterine cavity after childbirth, etc.п.

In order to prevent sepsis and enterocolitis in intrauterine infection or the risk of nosocomial infection in newborns Streptococcus bacteriophage is used as enemas 2 times a day for 5-7 days.

Interaction

The use of Streptococcus bacteriophage does not rule out the use of other medications, including antibiotics.

Special Instructions

Streptococcus bacteriophage liquid is not suitable for use in case of turbidity and the presence of flakes.

Pregnant use is possible by prescription with observance of the dose.

Contraindications

Individual intolerance.

Side effects

Reactions to streptococcal bacteriophage administration have not been established.