Stomatidine, 0.1% solution 200 ml

Stomatidine is an antiseptic drug for topical use in otorhinolaryngology and dentistry.

The antimicrobial action of hexatidine is associated with the inhibition of oxidative reactions of metabolism of microbial cells (thiamine antagonist). The drug has antibacterial action against Gram-negative and Gram-positive bacteria, Pseudomonas aeruginosa and Proteus spp. and antifungal action (including against fungi of the genus Candida). At a concentration of 100 mg/ml inhibition of growth of most bacterial strains is achieved. No development of resistance was observed.

Hexethidine has a weak analgesic effect on the mucosa.

Pharmacokinetics

Hexethidine adheres well to the mucosa and is practically not absorbed. After a single application, hexatidine is detectable on the oral mucosa for 65 hours. In dental plaques active concentrations persist for 10-14 hours after application.

Indications

Inflammatory and infectious diseases of the mouth and throat:

Active ingredient

Composition

1 ml of the solution contains:

acting substance:

hexetidine 1.00 mg,

supplements:

propylene glycol,

polysorbate-20,

citric acid monohydrate,

sodium saccharinate,

razenthol,

methylsalicylate,

p> azorubin dye,

Ethanol 96%,

water.

How to take, the dosage

Topically.

The undiluted product should always be used for gargling.

The solution must not be swallowed. The solution must be spit out after rinsing.

In case of oral diseases in adults and children over 5 years of age, rinse the mouth with 10-15 ml (one tablespoon) of undiluted solution of the drug for 30 seconds.

In case of throat diseases in adults and children over 5 years of age the same amount of undiluted solution of the drug is used to gargle for 30 seconds. In the treatment of diseases of the oral cavity the drug can be applied using a tampon.

Apply 2 times a day (preferably in the morning and evening), after meals.

The duration of application of the drug is determined individually. If the symptoms of the disease do not disappear after 5 days of using the drug and / or accompanied by fever it is necessary to see a doctor.

Interaction

No undesirable interaction of hexatidine with other drugs when applied topically has been noted.

It works synergistically with fluorides and zinc preparations.

Special Instructions

Do not use the drug in that category of patients who cannot perform this procedure (gargling) on their own.

Impact on the ability to drive vehicles or operate machinery.

No effect.

The drug contains 10% ethanol (96% ethyl alcohol).

The drug should be taken at least 30 minutes before starting to drive.

Contraindications

Side effects

Burning, irritation and moderate dryness of the oral mucosa, allergic reactions.

Long-term use may cause changes in taste sensation.

The side effects disappear after discontinuing the drug.

Overdose

Symptoms:Inadvertent ingestion of large amounts of the drug may cause nausea and vomiting.

Treatment:Gastric lavage, prescription of symptomatic therapy.

Pregnancy use

There are insufficient data on the penetration of hexatidine through the placenta and into the breast milk.

The drug may be used during pregnancy if the potential benefit to the mother exceeds the risk to the fetus.

If it is necessary to use the drug during lactation, it is necessary to consider stopping breastfeeding.

Similarities