Sporobacterin, 10 ml suspension

Bacillus subtilis bacteria strain 534 secrete broad-spectrum antibacterial substances that inhibit the development of a number of pathogenic and opportunistic bacteria. The growth of saprophytes, including normal gut microflora, is not inhibited by sporobacterin.

The culture of Bacillus subtilis strain 534 also produces other bioactive substances such as proteolytic enzymes, lysozyme, lipase, amylase and others contributing to the breakdown of carbohydrates, fats and proteins and taking part in digestion and assimilation of food.

In addition, bacterial enzymes help to clean wounds and inflammatory foci from necrotic tissues. The drug has a pronounced immunostimulatory effect, including on the absorption and digestive activity of phagocytic blood cells and has a moderate anti-allergic effect.

Indications

Sporobacterin is used to treat:

• acute bacterial intestinal infections, including acute dysentery, salmonellosis, etc.
• dysbacteriosis of various etiologies
• surgical infection of soft tissues
• osteomyelitis (in the absence of large sequestrations)

.

• for prevention and treatment of complications caused by pathogenic and opportunistic microorganisms in surgical and obstetric-gynecological operations.

Sporobacterin is prescribed for children over 6 months and adults.

Active ingredient

Bacillus subtilis

Composition

1 ml contains:

The biomass of live Bacillus subtilis 534 – not less than 1×10⁹ CFU.

Additives:

Sodium chloride 70 mg/ml,

Water purified to 1 ml.

How to take, the dosage

The prescribed dose of the drug is diluted 10-15 times with cooled boiled water. Sporobacterin is prescribed 30-40 minutes before meals.

For treatment of gastrointestinal tract diseases:

Children:

• for treatment of acute bacterial intestinal infections, including acute dysentery, salmonellosis: at the age of 6 months to 3 years old administer by mouth 0.5 ml (8-10 drops) two times a day for 7-10 days; over 3 years – 1 ml (17-20 drops) two times a day for 7-10 days
• For treatment of dysbacteriosis after bacterial infections or antibiotic treatment: 6 month to 3 years old administer by mouth 0.5 ml (8-10 drops) 2 times a day for 20 days, over 3 years – 1 ml (17-20 drops) 2 times a day for 20 days. If a nursing mother has dysbacteriosis, it is recommended to take 1 ml 2 times a day during the period of treatment of the child.

In adults:

• For the treatment of acute bacterial intestinal infections, including acute dysentery, salmonellosis: The drug is prescribed by mouth 1 ml (17-20 drops) 2 times a day for 7-10 days;
• to treat dysbacteriosis after bacterial infections or antibiotic use: the drug is prescribed by mouth 1 ml 2 times a day for 20 days.

in surgical practice:

• for the treatment and prevention of surgical soft tissue infection: the drug is administered by mouth 1 ml 2 times a day for 7-10 days;
• for prevention of purulent-septic complications in the postoperative period: the drug is administered by mouth 5 ml once daily (at night) for 5 days before surgery and 5 ml once daily (at night) for 5 days after surgery or injury.

The courses of treatment may be repeated if necessary.

! An opened vial of the drug, with the lid on, can be stored for up to 10 days at a temperature of 4 to 8°C.

Interaction

Simultaneous use of antibiotics and sulfonamides may reduce the therapeutic efficacy of sporobacterin.

Special Instructions

Ability to affect driving and operating machinery.

The use of the drug has no effect on driving and operating machinery.

Contraindications

There are no contraindications for the use of Sporobacterin. The drug should be used with caution in case of drug allergy. The effect of the drug on pregnant women has not been studied.

It is not suitable for use: the drug, the integrity of the packaging is broken; the product is unlabeled; the product with altered physical properties and the presence of foreign impurities.

Side effects

In rare cases, there may be side effects in the form of chills, skin rashes, abdominal pain, and diarrhea.

If the dose is decreased or the drug is discontinued, these effects subside within 24 hours.