Solpadein Fast, 65 mg+500 mg 12 pcs
€11.35 €9.93
Analgesic-antipyretic of the combined composition, contains a combination of two active ingredients: paracetamol and caffeine. It has antipyretic and analgesic effect.
Paracetamol blocks COX in the CNS, affecting the centers of pain and thermoregulation (in inflamed tissues cellular peroxidases neutralize the effect of paracetamol on COX), which explains the almost complete absence of anti-inflammatory effect.
Indications
Neuralgia, Toothache, Joint Pain (arthralgia), Fever, Flu, Myalgia (muscle pain), Headache, Painful menstruation (algodysmenorrhea), Acute respiratory infections
- Headache;
- migraine;
- dental pain;
- neuralgia;
- muscular and rheumatic pain;
- painful menstruation;
sore throat;
- symptomatic treatment of colds and flu (to reduce elevated body temperature).
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Active ingredient
Caffeine, Paracetamol
Composition
Active ingredients:
Paracetamol 500 mg; caffeine 65 mg.
Auxiliary substances:
sorbitol,
sodium saccharinate, <
sodium bicarbonate,
povidone, <
sodium lauryl sulfate,
dimethicone,
citric acid,
sodium carbonate.
How to take, the dosage
Solpadein Fast soluble tablets should be dissolved in at least 100 ml (half a glass) of water before oral administration.
Adults (including elderly) and children over 12 years are prescribed 1-2 tablets. 3-4 times a day, if necessary. The interval between doses is at least 4 hours. The maximum single dose is 2 tablets. The maximum daily dose is 8 tablets.
It is not recommended to apply the preparation for more than 5 days as analgesic and for more than 3 days as antipyretic without prescription and medical supervision.
Increase of daily drug dose or the duration of treatment is possible only under medical supervision.
Interaction
When taking regularly for a long time, the drug increases the effect of indirect anticoagulants (warfarin and other coumarins), which increases the risk of bleeding. Episodic use of a single dose of the drug has no significant effect on the effect of indirect anticoagulants.
The drug increases the effect of MAO inhibitors.
Barbiturates, carbamazepine, phenytoin, primidone, ethanol, rifampicin, phenylbutazone, preparations of Hypericum, tricyclic antidepressants and other inducers of microsomal oxidation increase production of hydroxylated active metabolites causing possible severe liver damage in small overdoses of paracetamol (5 g and more).
Inhibitors of microsomal oxidation (cimetidine) reduce the risk of hepatotoxic action.
Under the influence of paracetamol excretion time of chloramphenicol increases by 5 times.
Caffeine accelerates absorption of ergotamine.
Simultaneous administration of paracetamol and alcoholic beverages increases the risk of hepatotoxic effects and acute pancreatitis.
Metoclopramide and domperidone increase, and colestyramine reduces the absorption rate of paracetamol.
The drug may reduce the effectiveness of uricosuric drugs.
Special Instructions
If there is no improvement in the condition while taking the drug, or if the headache becomes permanent, you should consult a doctor.
Synopsis
Tablets are soluble white, flat, with a circumferentially cut edge and a rib on one side.
Contraindications
- Major liver dysfunction
- Major renal dysfunction
- arterial hypertension
- glaucoma;
- sleep disorders;
- Epilepsy;
- children under 12 years of age;
- high sensitivity to the components of the drug.
The drug should be used with caution in benign hyperbilirubinemia (including Gilbert syndrome), viral hepatitis, alcoholic liver injury, glucose-6-phosphate dehydrogenase deficiency, alcoholism.
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Side effects
In recommended doses, the drug is generally well tolerated.
Side effect frequency determination: very frequently (≥1/10), frequently (≥1/100 and < 1/10), infrequently (≥1/1000 and < 1/100), rarely (≥1/10 000 and < 1/1000), very rarely (≥1/100 000 and < 1/10 000).
The following side effects were detected spontaneously during post-registration use of the drug.
Paracetamol
Allergic reactions: very rare – skin rash, angioedema (Quincke’s edema), Stevens-Johnson syndrome, anaphylaxis.
Blood system: very rarely – leukopenia, thrombocytopenia, methemoglobinemia, agranulocytosis, hemolytic anemia.
Respiratory system: very rare – bronchospasm (in patients with hypersensitivity to acetylsalicylic acid and NSAIDs).
Hepatobiliary system: very rarely – liver function disorders.
In long-term use in high doses the possibility of hepatotoxic effect, nephrotoxic effect and pancytopenia increases.
Caffeine
Possible: dyspeptic complaints (including nausea, epigastric pain), increased excitability, dizziness, sleep disturbances, tachycardia.
If any of the above side effects occurs, the drug may cause anxiety, anxiety, irritability, insomnia, headache, disorders of the digestive system, tachycardia, cardiac arrhythmia.
Overdose
Symptoms due to paracetamol: pale skin, nausea, vomiting, anorexia, stomach pain may occur within 24 hours; after 1-2 days there may be signs of liver damage (pain in the liver area, increased liver enzymes activity). Impaired carbohydrate metabolism and signs of metabolic acidosis are possible. In adult patients, liver damage develops after ingestion of more than 10 g of paracetamol.
Pregnancy use
The drug Solpadein Fast contains caffeine. When taking caffeine there is a high risk of having a baby with low body weight, risk of spontaneous abortion.
Getting into breast milk, caffeine may have a stimulating effect on the baby who is breastfeeding.
Solpadein Fast should not be used in pregnancy and during lactation (breastfeeding).
Similarities
Migraineum
Weight | 0.050 kg |
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Shelf life | 4 years. Do not use after the expiration date printed on the package. |
Conditions of storage | Store out of reach of children at temperatures under 25°C. |
Manufacturer | GlaxoSmithKlein Dungarvan Limited, Ireland |
Medication form | instant tablets |
Brand | GlaxoSmithKlein Dungarvan Limited |
Other forms…
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