Solonex, drops 10 mg/ml 20 ml

Cetirizine, the active ingredient of the drug, is a metabolite of hydroxyzine, belongs to the group of competitive histamine antagonists and blocks H1-histamine receptors.

Indications

The drug is indicated in adults and children from 6 months and older for relief:

– nasal and ocular symptoms of year-round (persistent) and seasonal (intermittent) allergic rhinitis and allergic conjunctivitis: itching, sneezing, nasal congestion, rhinorrhea, lacrimation, conjunctival hyperemia;
– symptoms of chronic idiopathic urticaria.

Administration in children aged 6 to 12 months is possible only by prescription and under strict medical supervision.

Active ingredient

Cetirizine

How to take, the dosage

Orally, drip into a spoon or dissolve in water. The amount of water to dissolve the drug should correspond to the amount of liquid that the patient (especially a child) is able to swallow. The solution should be taken immediately after preparation. Adults 10 mg (20 drops) once daily.
Elderly patients
There is no need to reduce the dosage in elderly patients if renal function is not impaired.

Patients with renal insufficiency As cetirizine is eliminated from the body mainly by the kidneys, if there is no alternative treatment for patients with renal insufficiency the drug dosage regimen should be adjusted according to the renal function (CK value). CK for men can be calculated based on serum creatinine concentration in plasma according to the following formula:

CK (ml/min) = [140 – age (years)] × body weight (kg) /72 × CK serum (mg/dl)

CK for women can be calculated by multiplying the obtained value by coefficient 0,85.

Patients with hepatic dysfunction
In patients with hepatic dysfunction only the dosage regimen does not require correction. In patients with liver and kidney function disorders the dosage adjustment is recommended.

Children
Administration in children aged 6 to 12 months is possible only by prescription and under close medical supervision.
Children 6 to 12 months 2.5 mg (5 drops) once a day
Children 1 to 6 years old 2.5 mg (5 drops) twice a day
Children 6 to 12 years old 5 mg (10 drops) twice a day
Children over 12 years of age 10 mg (20 drops) once daily

Sometimes an initial dose of 5 mg (10 drops) may be sufficient if satisfactory symptom control can be achieved.

In children with renal insufficiency, the dose is adjusted for CK and body weight.

If no improvement occurs after treatment or symptoms worsen or new symptoms appear, consult a physician. Use the drug only according to the indications, the method of administration and in the doses specified in the instructions.

Interaction

Concomitant use with azithromycin, cimetidine, erythromycin, ketoconazole or pseudoephedrine does not affect the pharmacokinetic parameters of cetirizine.

Special Instructions

Due to the potential depressant effect on the central nervous system, caution should be exercised when prescribing the drug in children under 1 year of age if the following risk factors for sudden infant death syndrome are present, such as (but not limited to):
– sleep apnea syndrome or sudden infant death syndrome in a sibling;
– maternal drug or smoking abuse during pregnancy;
– young maternal age (19 years or younger);
– smoking abuse by a babysitter (one pack of cigarettes per day or more); <
– children who regularly fall asleep face down and are not placed on their backs;
– prematurely born (gestational age less than 37 weeks) or children born with low birth weight (below the 10th percentile of gestational age);
– when taking concomitant medications that have a depressant effect on the central nervous system.