Sodium sulfacyl, eye drops 20% 10 ml

An antibacterial agent for topical use in ophthalmology, a sulfonamide derivative. It has a wide range of antimicrobial action. It has a bacteriostatic effect.

The mechanism of action is connected with competitive antagonism with PABA and competitive inhibition of dihydropteroatsintase which leads to disruption of tetrahydrofolic acid synthesis which is necessary for purines and pyrimidines synthesis.

Sulfacetamide is active against Gram-positive and Gram-negative bacteria (including pathogenic cocci, Escherichia coli), Chlamydia spp.

Pharmacokinetics.

Indications

Purulent corneal ulcers, conjunctivitis, blepharitis, gonorrheal eye diseases in newborns and adults, prevention of blenorrhea in newborns.

Pharmacological effect

Antibacterial agent for topical use in ophthalmology, sulfanilamide derivative. Has a wide spectrum of antimicrobial action. Has a bacteriostatic effect.

The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidines.

Sulfacetamide is active against gram-positive and gram-negative bacteria (including pathogenic cocci, Escherichia coli), Chlamydia spp., Actinomyces spp.

Pharmacokinetics

Special instructions

Patients hypersensitive to furosemide, thiazide diuretics, sulfonylureas, or carbonic anhydrase inhibitors may be hypersensitive to sulfacetamide.

Active ingredient

Sulfacetamide

Composition

1 ml contains:

Active ingredient

sulfacetamide 200 mg.

Excipients:

sodium thiosulfate;

hydrochloric acid solution 1 M;

water for injections

Contraindications

Individual hypersensitivity to the components of the drug, children’s age (up to 2 months).

Side Effects

Local reactions: itching, redness, swelling.

Interaction

Sulfacetamide, when applied topically, is incompatible with silver salts.

Storage conditions

In a place protected from light, at a temperature not exceeding 25C.

Shelf life

2 years.

Manufacturer

Lecco CJSC, Russia