Sodium chloride, 0.90% 250 ml
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Sodium and chlorine ions are the most important inorganic components of extracellular fluid, maintaining the appropriate osmotic pressure of blood plasma and extracellular fluid. Isotonic solution replenishes fluid deficits in the body during dehydration. Hypertonic sodium chloride solution when administered intravenously provides correction of osmotic pressure of extracellular fluid and blood plasma. When used topically in ophthalmology sodium chloride has an anti-edema effect.
Restoration of water-salt balance
Isotonic solution: dehydration of different genesis. To maintain blood plasma volume during and after operations. As a solvent for various drugs.
Hypertensive solution: disorders of water-electrolyte exchange – deficiency of sodium and chlorine ions; hypoosmolar dehydration of various genesis (due to prolonged vomiting, diarrhea, burns; during gastric fistula, pulmonary bleeding, intestinal bleeding).
1000 ml of the solution contain:
Sodium chloride – 9.0 g
Water for injection – up to 1000 ml
Sodium – 154 mmol/L
Chloride – 154 mmol/L
Physical and chemical characteristics: Theoretical osmolarity 308 mOsm/L pH 4.5 – 7.0
How to take, the dosage
Individual, depending on indications, clinical situation, therapy regimen and applied dosage form.
Isotonic solution of sodium chloride is administered in the IV, n/a and in enemas, and also used for washing wounds, eyes, nasal mucosa. Depending on the clinical situation, up to 3 liters per day are administered by intravenous injection.
Hypertensive sodium chloride solution is administered by IV. A single dose for IV/injection by jet may be 10-30 ml. In conditions requiring immediate replenishment of sodium and chloride ions are administered by IV drops in a dose of 100 ml.
NSAIDs, androgens, estrogens, anabolic hormones, corticotropin, mineralocorticoids, vasodilators, ganglioblocators lead to increased Na+ retention.
With caution use large amounts of sodium chloride in patients with impaired renal excretory function, with hypokalemia. Administration of large amounts of the solution may lead to acidosis, hyperhydration, increased excretion of potassium from the body.
Hypertensive solution is not administered p/u and i/m.
On long-term use it is necessary to monitor the concentration of electrolytes in the plasma and daily diuresis.
The temperature of the infusion solution should be 38°C.
Hypersensitivity to sodium chloride; hypernatremia, conditions of hyperhydration, threat of pulmonary edema, brain edema.
Possible: nausea, vomiting, diarrhea, stomach cramps, thirst, lacrimation, sweating, fever, tachycardia, arterial hypertension, impaired renal function, edema, shortness of breath, headache, dizziness, restlessness, weakness, twitching and hypertonicity of muscles.
There have been no known adverse reactions when used topically or topically.
In pregnancy and during breastfeeding it is possible to use by indication in cases when the supposed benefit for a mother exceeds the potential risk for a fetus or an infant.
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|Conditions of storage|
At a temperature not exceeding 25 °C.
solution for infusion
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