Skin-cup, cream 0.2% 15 g

Pharmgroup: < br>

Preparation with antiproliferative, antibacterial and antifungal action for external use

Pharmaceutical action: < br>

Zinc pyrithione activated has anti-inflammatory, antibacterial and antifungal activity. Antifungal activity is especially expressed against Pityrosporum ovale and Pityrosporum orbiculare causing inflammation and excessive peeling in skin diseases. Antibacterial activity is shown against a number of pathogenic microorganisms Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp.

Zinc pyrithione reduces intracellular ATP level, promotes depolarization of cell membranes, causing death of fungi and bacteria. The mechanism of anti-inflammatory action is not studied.

Pharmacokinetics:

When applied externally, zinc pyrithione is deposited in the epidermis and superficial layers of the dermis. Systemic absorption occurs slowly. It is detected in the blood in trace amounts.

Indications

Psoriasis, atopic dermatitis, eczema, neurodermatitis, dry skin, seborrheic dermatitis in adults and children from 1 year old.

Composition

100 g of the drug contain: Active ingredient: activated zinc pyrithione 200 mg. Excipients: Glycerol mono- and distearate (Tegin M), capryl caprylate (Tegosoft EE), methyldextrose and macrogoal-20 ester (Tegosoft E20), isopropyl palmitate (Tegosoft P), methyldextrose polyglyceryl distearate (Tego Care 450), butylhydroxytoluene, glycerol, propyl parahydroxybenzoate (Nipagin), sucrose and coconut oil fatty acids ester (Tegosoft LSE 65K), stearyl alcohol (Tego Alcanol 18), ethanol, fragrance (citronellol, phenylethanol, geraniol, terpineol, cinnamon alcohol), cyclomethicone (Abil K 4), water.

How to take, the dosage

Externally. After shaking vigorously, the cream is applied thinly to the affected skin areas 2 times a day. Course of treatment for psoriasis 1-1.5 months, atopic dermatitis 3-4 weeks. Dosage and administration in pediatrics: The method of administration and dosage in children is the same as in adults. If necessary, repeat course of treatment in 1-1.5 months after consultation with a physician.

Special Instructions

In case of contact with eyes, rinse them with plenty of cold water.

Contraindications

Hypersensitivity to the ingredients of the drug.

Side effects

Allergic reactions. In the first days of treatment a brief burning sensation at the application site is possible, which usually does not require cancellation of the drug.

Pregnancy use

In pregnancy and during lactation the drug should be administered only in cases when the expected benefit of therapy for the mother exceeds the potential risk for the fetus or the infant.

No adverse effects have been reported with the use of zinc pyrithione in pregnant and breastfeeding women.