Sinekod, syrup 1.5 mg/ml 100 ml

Anti-cough drug of central action, does not relate to opium alkaloids neither chemically nor pharmacologically.

Indications

Symptomatic treatment of dry cough of various etiologies: cough suppression in the pre- and postoperative period, during surgery, bronchoscopy, whooping cough.

Active ingredient

Butamirate

Composition

Active ingredient:

Butamirate citrate – 0.150 (1.5 mg/ml).

Auxiliary substances:

Sorbitol solution 70% m/m 40.50,

Glycerol 29.00.

Sodium saccharinate 0.06,

Benzoic acid 0.115,

vanillin 0.06,

Ethanol 96% vol./ vol. 0.25,

sodium hydroxide 30% m/m 0.031,

water up to 100 ml.

How to take, the dosage

Orally, before meals.

Syrup (measured with measuring cap): Children from 3 to 6 years – 5 ml 3 times a day, 6-12 years – 10 ml 3 times a day, 12 years and older – 15 ml 3 times a day; adults – 15 ml 4 times a day.

Use the measuring cap (supplied).

The measuring cap should be washed and dried after each use. If the cough persists for more than 7 days, you should consult a doctor.

Interaction

Drug interaction of butamirate has not been described.

Due to the fact that butamirate suppresses the coughing effect, simultaneous use of expectorants should be avoided to avoid sputum accumulation in the airways with the risk of bronchospasm and respiratory tract infection.

Special Instructions

The syrup and the drops for oral administration contain saccharinate and sorbitol as sweeteners, therefore the drug may be administered to patients with diabetes.

The drug contains a small amount of ethanol: syrup – 11.73 mg/5 ml, drops for oral administration – 2.81 mg/ml. That is why the drug should be used with caution in patients with predisposition to drug addiction, with liver diseases, alcoholism, epilepsy, brain diseases, in pregnant women (II and III trimesters) and in children.

It should be taken into consideration when using the drug.

Effect on driving and operating machinery

Sinekod® may cause drowsiness, so caution should be exercised when driving vehicles and performing work requiring concentration (e.g., when working with mechanisms) after taking the drug.

Synopsis

Syrup (vanilla) in the form of a colorless clear liquid with a smell of vanilla.

Contraindications

Hypersensitivity; children under 3 years of age (for children under 3 years, Sinecod drops for oral administration for children can be used).

With caution: pregnancy (II and III trimesters).

Side effects

Definition of the frequency of side effects: very frequently (≥1/10), frequently (≥1/100 and < 1/10), infrequently (≥1/1000 and < 1/100), rarely (≥1/10 000 and < 1/1000), very rarely (< 1/10 000), including individual reports.

Nervous system: rarely – drowsiness.

Digestive system: rarely – nausea, diarrhea.

Allergic reactions: rarely – urticaria, other manifestations are possible.

Overdose

Symptoms: drowsiness, nausea, vomiting, diarrhea, dizziness and decreased blood pressure.

Treatment: gastric lavage, administration of activated charcoal, maintenance of vital body functions. There is no special antidote.

Pregnancy use

Controlled clinical trials in pregnant women have not been conducted.

In this regard, Sinekod® should not be used in the first trimester of pregnancy. In II and III trimesters Sinecod® administration is possible taking into account the benefit for the mother and the potential risk for the fetus.

Given the lack of data on excretion of butamirate with breast milk, administration of the drug during lactation is not recommended.
In animal studies no adverse effects on fetus were noted.

Similarities

Omnitus, Codelac Neo