Sinaflan, 0.025% ointment 15 g

Pharmaceutical group:

Glucocorticosteroid for topical use.

Pharmic action:

Synaflan has anti-inflammatory, anti-allergic, antiexudative and antipruritic effects.

It reduces manifestations and eliminates inflammatory skin reactions.

Pharmacokinetics:

After absorption from the skin surface, it binds to plasma proteins and undergoes metabolism, occurring mainly in the liver. It is excreted through the kidneys.

Indications

– Eczema,

— atopic dermatitis,

— simple chronic lichen (limited neurodermatitis),

— toxicodermy,

— simple allergic dermatitis,

— seborrheic dermatitis,

— skin itching,

– urticaria,

— pruritus,

— diaper rash,

— exudative erythema multiforme,

— psoriasis (exudative form);

— lichen planus,

— discoid lupus erythematosus,

— hand dyshidrosis,

— external otitis,

— burns of the 1st degree,

– insect bites.

Pharmacological effect

Pharmaceutical group:

glucocorticosteroid for local use.

Pharmaceutical action:

Sinaflan has anti-inflammatory, antiallergic, antiexudative and antipruritic effects.

Reduces symptoms and eliminates inflammatory skin reactions.

Pharmacokinetics:

After absorption from the surface of the skin, it binds to plasma proteins and undergoes metabolism, which occurs mainly in the liver. Excreted through the kidneys.

Special instructions

Use only in short courses on small areas of skin.

The drug should not be applied to the face. Avoid getting the drug into your eyes.

The duration of administration in children should not exceed 5 days. It is recommended to wear loose clothing during treatment.

In patients with acne vulgaris or rosacea, the disease may worsen during treatment.

To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

Without a doctor’s prescription.

Active ingredient

Fluocinolone acetonide

Active components

Fluocinolone acetonide

Composition

1 g ointment contains:

Active ingredient:

Fluocinolone acetonide (sinaphlan) – 0.25 mg,

Excipients:

Propylene glycol – 49.75 mg,

Ceresin – 50.00 mg,

Lanolin – 50.00 mg,

Vaseline – up to 1.0 g.

Contraindications

Hypersensitivity to the components of the drug; bacterial, viral, fungal skin diseases – pyoderma, chicken pox, herpes, actinomycosis, blastomycosis, sporotrichosis; skin manifestations of syphilis,

skin tuberculosis, diaper rash, rosacea, extensive psoriatic rashes (plaques), anogenital itching; trophic ulcers of the leg associated with varicose veins, erosive and ulcerative lesions of the gastrointestinal tract

intestinal tract, wounds at application sites; skin cancer, nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma; pregnancy and lactation period, children’s age (up to 2 years).

Use with caution in girls during puberty.

Side Effects

The development of secondary infectious skin lesions and atrophic changes in it (burning, itching, dry skin, steroid acne, folliculitis) is possible.

With long-term use – hypertrichosis, alopecia, especially in women, secondary immunodeficiency (exacerbation of chronic infectious diseases, generalization of infectious

process, development of opportunistic infections); skin atrophy, local hirsutism, telangiectasia, purpura, pigmentation disorder.

When applied to large surfaces, systemic manifestations are possible (gastritis, “steroidal” gastric ulcer, adrenal insufficiency, Itsenko-Cushing syndrome, “steroidal” diabetes mellitus, slowdown of reparative processes).

Interaction

Compatible with antimicrobial agents.

Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations.
Diuretics (except potassium-sparing drugs) increase the risk of hypokalemia.

Overdose

Itching, burning of the skin at the site of application of the ointment; with long-term use over a large surface of the body, hyperglycemia, glucosuria, Itsenko-Cushing syndrome. Treatment: symptomatic with gradual withdrawal of the drug.

Recommendations for use

Externally.

A small amount of the drug is applied to the skin, previously wiped with a swab moistened with an antiseptic liquid, 2-4 times a day and lightly rubbed.

If necessary, you can apply an occlusive dressing, leaving it on the affected surface for up to 3-4 days. It is not allowed to apply more than 2 g per day under a bandage.

The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease up to 25 days.
The ointment is preferable to use for dry forms of dermatoses.

Prescribing

Glucocorticosteroid for local use

Complete set of goods

Ointment for external use 0.025%.

10 g or 15 g in aluminum or polyethylene laminate tubes.

Each tube, along with instructions for medical use of the drug, is placed in a cardboard box.

Functional features

After absorption from the skin surface, it binds to plasma proteins and is metabolized in the liver to form inactive metabolites.

Storage conditions

In a dry place, out of reach of children, at a temperature not exceeding 15 °C.

Shelf life

5 years. Do not use the drug after the expiration date.

Manufacturer

Nizhpharm JSC, Russia