Sialor Rhino, 0.025% drops 5 pcs.

Oxymetazoline belongs to the group of alpha-adrenergic stimulants for local use. It has a vasoconstrictor effect. When administered intranasally it reduces swelling of the mucous membrane of the upper airways and nasal secretions.

Restores nasal breathing. Elimination of nasal mucous membrane edema helps restore aeration of paranasal sinuses, middle ear cavity which reduces the probability of bacterial complications (maxillary sinusitis, sinusitis, otitis media).

In local intranasal application in therapeutic concentrations it does not irritate and does not cause nasal mucous membrane hyperemia. The drug starts to work quickly, within a few minutes. The duration of action of the drug is up to 12 hours.

Pharmacokinetics< br>

In local intranasal administration, oxymetazoline has no systemic action. The half-life of oxymetazoline when administered intranasally is 35 hours. 2.1% of oxymetazoline is excreted with urine and about 1.1% with feces.

Indications

Active ingredient

Composition

How to take, the dosage

Intranasally.

The drug is not recommended for more than 7 days. Frequent and prolonged use may cause nasal congestion or worsen it. If these symptoms occur, discontinue treatment and consult a physician.

Interaction

In concomitant use with monoamine oxidase inhibitors (including the period within 14 days after their withdrawal), tricyclic antidepressants or other drugs that contribute to increased blood pressure, increased blood pressure may be observed. The drug slows absorption of local anesthetic drugs, prolonging their effect.

The co-administration of other vasoconstrictors increases the risk of side effects.

If you are using the above or other medications (including over-the-counter medications), please consult your physician before using Cialor®rino.

Special Instructions

Use in the recommended dose without consulting a physician for no more than 7 days. If symptoms worsen or do not improve within 3 days, consult a physician. Avoid contact with eyes.

The drug should be used individually to avoid spreading infection. After opening, use within 14 days.

Long-term use and overdose of oxymetazoline may weaken the therapeutic effect and increase the risk of reactive hyperemia (medicated rhinitis) and atrophy of the nasal mucosa.

After long-term use of rhinitis remedies containing oxymetazoline in doses higher than recommended, the overall effect on the cardiovascular system and the central nervous system cannot be excluded. In these cases, caution is recommended when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and rapid psychomotor reactions.

Contraindications

In patients with increased intraocular pressure, patients with diseases of the cardiovascular system (arterial hypertension, coronary heart disease, chronic heart failure, tachycardia, arrhythmias), disorders of carbohydrate metabolism (diabetes), Thyroid disorders (hyperthyroidism), pheochromocytoma, chronic renal insufficiency, prostatic hyperplasia (urinary retention), significant atherosclerosis, porphyria, pregnancy, breastfeeding, and patients taking tricyclic antidepressants and bromocriptine.

Side effects

Burning or dry mucous membranes of the nasal cavity, dry mucous membranes of the mouth and throat; sneezing; increased nasal secretion, nasal bleeding; after the effect of the drug passes, a strong feeling of “stuffy” nose (reactive hyperemia).

Side effects due to the systemic action of the drug: increased blood pressure, headache, dizziness, palpitations, tachycardia, anxiety, restlessness, fatigue, sleepiness, sedation, irritability, sleep disturbances (in children), nausea, insomnia, exanthema, visual disturbances (when in the eyes), hallucinations, Quincke’s edema, itching, seizures, respiratory arrest (in infants). With long-term use – tachyphylaxis, reactive mucosal hyperemia and atrophy of the nasal mucosa.

The preservative benzalkonium chloride contained in the drug may cause nasal mucosal edema. If this happens, you need to change the product for one that does not contain preservatives.

If you have any of the side effects mentioned in the leaflet, or if they get worse, or if you notice any other side effects not mentioned in the leaflet, tell your doctor.

Overdose

Inadvertent ingestion or overdose may cause the following symptoms: anxiety, restlessness, hallucinations, seizures, decreased body temperature, lethargy, drowsiness, coma, constriction or dilation of pupils, fever, sweating, pallor, cyanosis, palpitation, bradycardia, arrhythmia, cardiac arrest, increased blood pressure, lower blood pressure, nausea, vomiting, depressed respiration, respiratory arrest.

Treatment: symptomatic. In case of accidental ingestion – gastric lavage, intake of activated charcoal. Vasopressor drugs are contraindicated.

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