Senade, tablets 13.5 mg 500 pcs

Laxative of vegetable origin.

It has a laxative effect that occurs after 8-10 hours.

The laxative effect is due to the effect on the receptors of the large intestine, increasing peristalsis.

Indications

Contipation caused by hypotension and sluggish peristalsis of the large intestine.

Stool regulation in hemorrhoids, proctitis, anal fissures.

Active ingredient

Sennosides A & B

Composition

Active ingredient:

Senna leaf extract dry 90.0 mg (containing the sum of calcium salts of senosides A and B converted to senoside B – 13.5 mg)

Auxiliary substances:

Lactose -23.07 mg

Starch 43.56 mg

Methyl parahydroxybenzoate – 0,04 mg

Microcrystalline cellulose – 15,0 mg
Cellulose

Talc – 11,13 mg

Magnesium stearate – 0,93 mg

Sodium lauryl sulfate -0,93 mg

Sodium Carmellose – 2,00 mg

How to take, the dosage

Take orally usually once a day in the evening before bedtime with water or some beverage.

Adults and children over 12 years: 1 tablet at a time.

If there is no effect, the dose can be increased to 2-3 tablets.

Children 6-12 years of age: 1/2 tablet and if necessary, increase the dose to 1-2 tablets.

In the fitting process, the same dose should be taken over several days and gradually increased by 1/2 tablet.

If defecation does not occur within 3 days after reaching the maximum dose, a doctor should be consulted.

Interaction

In long-term use of Senade in high doses it is possible to increase the effect of cardiac glycosides and influence on the effect of antiarrhythmic drugs due to the possibility of hypokalemia.

In concomitant use with thiazide diuretics, glucocorticoids, licorice root preparations, the risk of hypokalemia increases.

Special Instructions

It is not recommended to use the drug for more than 2 weeks.

The urine may turn yellow-brown or red-lilac after taking the drug.

Contraindications

• spastic constipation;

• intestinal obstruction;

• abdominal pain of unclear genesis;

• strangulated hernia; acute inflammatory diseases of the abdomen;

• peritonitis peritonitis;

• gastrointestinal and uterine bleeding;

• cystitis;

Side effects

Digestive system:

possible colic-like abdominal pain, flatulence; with prolonged use, especially in high doses, melanin deposition in the intestinal mucosa, nausea, vomiting, diarrhea are possible.

Metabolism disorders:

with prolonged use, especially in high doses, disorders of water-electrolyte metabolism, deposition of melanin in the intestinal mucosa are possible.

Since the urinary system:

long-term use, especially in high doses may cause albuminuria, hematuria, urine discoloration.

CNS side:

convulsions, fatigue, confusion are possible during long-term use, especially in high doses.

Dermatological reactions:

in prolonged use, especially in high doses, skin rash is possible.

Cardiovascular system:

vascular collapse is possible with prolonged use, especially in high doses.

Overdose

The main adverse effect in overdose is diarrhea leading to dehydration.

The conservative measure is to increase fluid intake. This is usually enough to compensate for fluid and electrolyte loss.

In some cases, it is necessary to compensate for fluid and electrolyte loss with intravenous infusions of plasma substitutes.

Similarities

Senadexin