Selank, drops 0.15% 3 ml

Pharmacotherapeutic group:

Anxiolytic medicine (tranquilizer).

The ATX code: N05BX

Pharmacological action

Pharmacodynamics

Selank® is a synthesized analogue of the endogenous peptide taftzin and has an original mechanism of neurospecific action on the central nervous system.

Selank® has an anti-anxiety action with antidepressant effect; antiasthenic action.

It relieves symptoms of anxiety, worry, fear, apathy, depression and asthenia.

It has a positive effect on cognitive functions, improves memory, speech, increases attention, stimulates learning processes, in particular the memorization, analysis and reproduction of information. It normalizes psychomotor reactions.

In cases of stress, Selank® eliminates the emotional and negative tension and stimulates the development of adaptive behavior aimed at achieving beneficial results.

Pharmacokinetics

Selank® is administered intranasally (nasal drops). Absolute bioavailability of Selank® when administered to the nasal mucosa is 92.8%. The drug is quickly absorbed from the nasal mucosa and after 30 seconds is detected in blood plasma, and then rapidly distributed to various organs and tissues. It penetrates into brain tissues. The plasma concentration decreases progressively within 5-5.5 minutes. In daily urine no unchanged drug or metabolites are determined due to rapid degradation of Selank® under the influence of tissue peptidases.

Indications

Alarm states:

unmotivated anxiety, restlessness;

panic attacks;

neurasthenia;

asthenia;

mood instability;

sleep disorders;

decreased willpower, initiation of activities, indecisiveness, difficulties in making decisions, lack of self-confidence;

lack of confidence in communication;

adjustment disorders;

Prevention and treatment of stress disorders.

Pharmacological effect

Pharmacotherapeutic group:

anxiolytic drug (tranquilizer).

ATX code: N05BX

Pharmacological action

Pharmacodynamics

Selank® is a synthesized analogue of the endogenous tuftsin peptide, which has an original mechanism of neurospecific action on the central nervous system.

Selank® has an anti-anxiety effect with an antidepressant effect; antiasthenic effect.

Relieves symptoms of restlessness, anxiety, fear, apathy, depression and asthenia.

It has a positive effect on cognitive functions, improves memory, speech, increases attention, activates learning processes, in particular, memorization, analysis and reproduction of information. Normalizes psychomotor reactions.

In case of stress, Selank® eliminates emotional and negative tension and stimulates the development of adaptive behavior aimed at achieving a useful result.

Pharmacokinetics

Selank® is administered intranasally (nasal drops). The absolute bioavailability of Selank® when administered to the nasal mucosa is 92.8%. The drug is quickly absorbed from the nasal mucosa and after 30 seconds is detected in the blood plasma, and then quickly distributed to various organs and tissues. Penetrates into brain tissue. Plasma concentrations decrease progressively over 5-5.5 minutes. Neither unchanged drug nor metabolites are detected in daily urine, which is due to the rapid degradation of Selank® under the influence of tissue peptidases.

Special instructions

Impact on the ability to drive vehicles and other mechanisms that require increased concentration

The absence of hypnosedative and muscle relaxant properties of the drug and the presence of a positive effect on cognitive functions make it possible to use Selank in people of various professions, including those requiring increased attention and coordination of movements (vehicle drivers, operators).

Active ingredient

Threonyl-Lysyl-Prolyl-Arginyl-Prolyl-Glycyl-Proline

Composition

Composition per 1 ml:

Pregnancy

Contraindicated during pregnancy and lactation.

Contraindications

Individual intolerance to the drug.

Pregnancy, breastfeeding (efficacy and safety studies have not been conducted).

Children under 18 years of age (efficacy and safety studies have not been conducted).

Side Effects

With increased sensitivity to the perception of smell and taste, unpleasant taste sensations may appear when the drug gets from the nasal cavity onto the mucous membrane of the pharynx. It is possible to develop allergic reactions due to individual intolerance.

If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

Selank® does not affect the effects of drugs that depress and stimulate the central nervous system – haloperidol, pentobarbital, hexobarbital, analeptics.

Selank® can be combined with any psycho- and neuroactive therapy.

Selank® is safe when used together with ethanol-containing products.

If you are taking other medications (including over-the-counter medications), consult your doctor before using Selank®.

Overdose

No cases of overdose have been reported when using the drug Selank®.

Storage conditions

Store in a place protected from light, at a temperature not exceeding 10 C.

Do not freeze. Store the opened bottle at a temperature not exceeding 25 C for no more than 15 days.

Keep out of the reach of children.

Shelf life

2 years.

Manufacturer

Peptogen, Russia