Sanorin with menthol and eucalyptus, spray 0.1% 10 ml

Pharmacotherapeutic group: Antinoconstrictive agent – alpha-adrenomimetic.< br>

Pharmacodynamics

Nafazolin is an alpha-adrenergic stimulant with fast, expressed and prolonged vasoconstrictor effect against the vessels of mucous membranes of the nasal cavity, nasopharynx and accessory sinuses – it reduces swelling, hyperemia and exudation improving nasal passageway patency and facilitating nasal breathing. At the same time the patency of the eustachian tubes is restored.< br>

Therapeutic effect usually comes within 5 minutes after the introduction of the drug and lasts for 4-6 hours. Tolerance occurs after 5-7 days.< br> The menthol and eucalyptol contained in the drug have a cooling effect on the nasal mucosa giving a feeling of freshness.

Pharmacokinetics

When used topically, systemic absorption is low. The vasoconstrictor effect occurs within a few minutes and lasts for several hours.

Indications

Acute rhinitis (including against the background of acute respiratory diseases and allergic rhinitis), sinusitis, eustachitis, laryngitis, laryngeal edema of allergic origin, laryngeal edema due to radiation, hyperemia of the mucous membrane after operations on the upper respiratory tract.

To stop nosebleeds.

To facilitate rhinoscopy.

Pharmacological effect

Pharmacotherapeutic group: Anticongestant – alpha-adrenergic agonist.

Pharmacodynamics

Naphazoline is an alpha-adrenergic stimulating agent that has a rapid, pronounced and long-lasting vasoconstrictor effect on the vessels of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses – it reduces swelling, hyperemia, exudation, thereby improving the patency of the nasal passages and facilitating nasal breathing. Along with this, the patency of the Eustachian tubes is restored.

The therapeutic effect usually occurs within 5 minutes after administration of the drug and lasts for 4-6 hours. After 5-7 days, tolerance occurs.
The menthol and eucalyptol contained in the preparation have a cooling effect on the nasal mucosa, giving a feeling of freshness.

Pharmacokinetics

When applied topically, systemic absorption is low. The vasoconstrictor effect occurs within a few minutes and continues for several hours.

Special instructions

May have a resorptive effect.

With long-term use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended to take a break for several days after 5-7 days of use.

Due to the possible development of side effects from the cardiovascular and nervous systems, the dose of the drug recommended for use should not be exceeded.

Avoid contact of the drug with the eyes.

To avoid the spread of infection, it is necessary to use the drug individually.

Active ingredient

Naphazoline

Composition

Composition of the drug per 1 ml:

Active ingredient:

Naphazoline nitrate 1.0 mg

Excipients:

Boric acid 16.0 mg

Sorbitol liquid (non-crystallizing) 14.0 mg

Macrogol glyceryl hydroxystearate 2.5 mg

Levomenthol 0.3 mg

Cineole (eucalyptol) 0.2 mg

Water for injections up to 1 ml.

Pregnancy

Use for the treatment of pregnant women and during breastfeeding is possible only if the expected benefit to the mother outweighs the potential risk to the fetus and child.

Contraindications

Hypersensitivity to the components of the drug, arterial hypertension, severe atherosclerosis, hyperthyroidism, severe eye diseases, angle-closure glaucoma, chronic rhinitis, atrophic rhinitis, children under 18 years of age, diabetes mellitus, tachycardia, simultaneous use of monoamine oxidase inhibitors and a period of up to 14 days after the end of their use.

With caution

Coronary heart disease (angina), prostatic hyperplasia, pheochromocytoma, pregnancy, breastfeeding.

Side Effects

Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa, irritation, when used for more than 1 week – swelling of the nasal mucosa, atrophic rhinitis.

Interaction

Should not be used concomitantly with monoamine oxidase inhibitors or within 14 days after stopping their use.

Slows down the absorption of local anesthetic drugs (prolongs their effect during superficial anesthesia).

Overdose

Symptoms: decreased body temperature, bradycardia, increased blood pressure.

Treatment: symptomatic.

Storage conditions

At a temperature not exceeding 25 °C.

Keep out of the reach of children.

Shelf life

4 years.

Do not use after the expiration date!

Manufacturer

Grotex LLC, Russia