Sanguiritrin, 5 mg 30 pcs.

Sanguiritrin is obtained from Macleaya cordata (Willd.) R.Br. and Macleaya microcarpa (Maxim.) Fedde in the poppy family Papaveraceae. Sanguiritrin is a mixture of bisulfates of two quaternary benzophenantridine alkaloids similar in structure and properties, sanguinarine and heleritrin.

Indications

In the complex therapy of acute and chronic purulent-inflammatory diseases: acute intestinal infections (dysentery, salmonellosis, food poisoning), wound infections and various infectious complications caused by pathogenic microflora (convalescent bacterial carriage), diseases associated with disruption of normal microflora (dysbacteriosis), as well as diseases caused by pathogenic fungi (pharyngomycosis, candidiasis, microsporia).

Pharmacological effect

Sangviritrin is obtained from the herb Macleaya cordata (Willd.) R.Br. and Macleaya microcarpa (Maxim.) Fedde of the poppy family – Papaveraceae. Sanguiritrine is a mixture of bisulfates of two quaternary benzophenanthridine alkaloids, sanguinarine and chelerythrine, which are similar in structure and properties.

Special instructions

Information for patients with diabetes:

Active ingredient

Sangviritrin

Composition

Composition per tablet:

Active substance:

Sanguiritrin® in terms of 100% substance (Sanguinarine hydrosulfate + Chelerythrine hydrosulfate) – 0.005 g,

Excipients (core):

Sugar (sucrose) or refined sugar, low molecular weight povidone (low molecular weight medical polyvinylpyrrolidone 12600 ± 2700), magnesium stearate – until a core weighing 0.100 g is obtained,

Shell excipients:

opadry II white OY-LS-28911, acrylise white 93018359, opadry II red 85F25163 – to obtain a film-coated tablet weighing 0.110 g.

Notes.
1. Composition of Opadry II white OY-LS-28911.
Hydroxypropyl methylcellulose (hypromellose) 28-40%
Lactose monohydrate 21-40% or
Polydextrose 21-40%
Polyethylene glycol 4000 (macrogol-4000) 8-14%
Dye – titanium dioxide 20-30%
2. Composition of white acrylic 93018359.
Copolymer of methacrylic acid with ethyl acrylate 1:1 40.0%
Titanium dioxide 15.0%
Talc 37.25%
Triethyl citrate 4.8%
Colloidal silicon dioxide anhydrous 1.25%
Sodium bicarbonate 1.2%
Sodium lauryl sulfate 0.5%
3. Composition of oprad II red 85F25163.
Hydroxypropyl methylcellulose (hypromellose) 28-40%
Lactose monohydrate 21-40% or Polydextrose 21-40%
Polyethylene glycol 4000 (macrogol-4000) 8-14%
Dye – iron oxide red, E 172 20-30%

Contraindications

Hypersensitivity to the components of the drug, epilepsy, hyperkinesis, bronchial asthma, coronary heart disease, severe liver and kidney diseases with impaired function. Children up to 3 years old.

Side Effects

Allergic reactions may occur.

Overdose

In case of an overdose of the drug, nausea, vomiting, abdominal pain, dizziness, and headache are possible.

Storage conditions

List B. In a dry place, protected from light, at a temperature not exceeding 25 ° C.

Shelf life

3 years

Manufacturer

Pharmcenter VILAR JSC, Russia