Salofalc, rectal dosed foam 1 g/application 14 pcs

How to take, the dosage

Unless otherwise prescribed by a physician, in adults and children over 12 years of age the drug is usually administered once a day before bedtime (1 dose corresponds to 2 applications/pressures). If it is difficult to retain this amount of foam in the colon, the drug should be administered in two steps: 1 time at night, and 1 more time at night or early in the morning (after defecation).

Injection after bowel movement (defecation) is recommended for best results.

At the time of administration Salofalk rectal foam must be at room temperature (20-25 °C).

1. Set the applicator firmly on the head of the can
2. Shake the can for 20 seconds to mix the contents
3. On first use, remove the protective tab from the base of the dispensing head.
4. Turn the cap, so that the round cut on the safety ring aligns with the nozzle
5. Place your index finger on the cap and turn the bottle upside down
6. Push the applicator as far into the rectum as possible. It is best to put your foot on a chair or stool. To inject the first part of the dose, press the cap as far as it will go and slowly release it. To administer the second part of the dose of the drug, press the cap again and slowly release it. Wait 10-15 seconds, then slowly remove the applicator from the rectum.
7. After administering the foam, remove the applicator and throw it away, packing it in a plastic bag. For each new dose of product, a new applicator should be used.
8. After the procedure, wash your hands. You should try not to empty your bowels until the next morning.

If you are admitted to the hospital or consult with other doctors, you should tell them about the use of this medication.

Therapeutic effect is achieved with regular use of Salofalc rectal foam.

The duration of the course of treatment is chosen by the doctor individually.

As a rule, an exacerbation of mild forms of ulcerative colitis can be stopped within 4-6 weeks. After this period, it is recommended to visit the attending physician to decide on the prescription of oral form of mesalazine for maintenance therapy.

Interaction

When concomitant administration may increase the effect of coumarin anticoagulants, increased toxicity of methotrexate, decreased diuretic effect of spironolactone and furosemide, decreased effectiveness of probenecid and rifampicin.

It increases hypoglycemic effect of oral antidiabetic agents – sulfonylurea derivatives.

Special Instructions

Salofalc is recommended to be used only under the supervision of a doctor.

Blood and urine tests should be performed before treatment, during therapy (14 days after the start of therapy and then every 4 weeks), and after the end of therapy (every 3 months).

In order to control kidney function it is recommended to determine serum urea and creatinine levels, urine sediment examination.

Contraindications

• Hypersensitivity to the drug components and other salicylic acid derivatives;
• blood diseases;
• duodenal and gastric ulcer;

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• glucose-6-phosphate dehydrogenase deficiency;
• hemorrhagic diathesis;
• severe renal/liver failure;
• childhood (under 6 years);
• phenylketonuria.

With caution: pregnancy (1st trimester), mild to moderate renal/liver failure, lung diseases (especially bronchial asthma).

Side effects

Gastrointestinal disorders: diarrhea, nausea, abdominal pain, flatulence, loss of appetite, vomiting, increased level of liver enzymes in blood, hepatitis.

CNS disorders: headache, depression, dizziness, sleep disturbance, malaise, paresthesias, seizures, tremors, tinnitus.

Reactions associated with hypersensitivity: skin rash, itching, erythema, fever, bronchospasm, pericarditis and myocarditis, acute pancreatitis, interstitial nephritis, nephrotic syndrome.

In isolated cases of allergic alveolitis and pancolitis have been observed. Under certain conditions, mesalazine and drugs with a similar chemical structure may lead to the development of a syndrome similar to systemic lupus erythematosus.

Other side effects: rarely – tachycardia, arterial hypertension or hypotension, pain behind the chest, shortness of breath; myalgia, arthralgia. In individual cases proteinuria, hematuria, crystalluria, oliguria, anuria; anemia, leukopenia, agranulocytosis, thrombocytopenia, hypoprothrombinemia; decreased tear fluid production, alopecia.

Overdose

Symptoms: nausea, vomiting, weakness, drowsiness.

Treatment: symptomatic therapy.

Pregnancy use

In case of pregnancy, suspected pregnancy, pregnancy planning, breastfeeding, consult the attending physician. The drug should not be used in the last 4 weeks of pregnancy.

Salofolk may be used during pregnancy only if the potential benefit to the mother exceeds the possible risk to the fetus.

You should not use rectal forms of the drug while breastfeeding – the active substance and its metabolites may penetrate into the breast milk. If it is necessary to prescribe Salofalk during lactation, the question of stopping breastfeeding should be decided.

Similarities

Salofalc, Mesacol, Mesalazine, Mesavant, Cansalazine