Salbutamol-Pharmstandart, aerosol 100 mcg/dose 200 doses
€4.88 €4.33
Salbutamol is a selective β2-adrenoreceptor agonist (β2-adrenomimetic). In therapeutic doses it acts on β2-adrenoreceptors of bronchial smooth muscle, having little or no effect on β1-adrenoreceptors of the myocardium.
It has a pronounced bronchodilator effect, preventing or arresting bronchial spasm, reduces resistance in the airways. Increases the vital capacity of the lungs. Increases mucociliary clearance (in chronic bronchitis up to 36%), stimulates mucus secretion, activates the functions of the intermittent epithelium.
In recommended therapeutic doses does not have adverse effects on the cardiovascular system, does not cause an increase in blood pressure. To a lesser extent compared to the drugs of this group, it has positive chrono- and inotropic effects. It causes dilation of the coronary arteries.
It has a number of metabolic effects: it reduces the concentration of potassium in the blood plasma, affects glycogenolysis and insulin release, has hyperglycemic (especially in patients with bronchial asthma) and lipolytic effects, increases the risk of acidosis.
After using an inhaled dose of salbutamol, the action develops quickly, the beginning of the effect – in 5 minutes, the maximum effect – in 30-90 minutes (75% of the maximum effect is reached within 5 minutes), duration – 4-6 hours.
Indications
Bronchial asthma, Bronchospasm, Learning Disabilities
1. Bronchial asthma:
– control of bronchial asthma attacks, including severe bronchial asthma exacerbations;
– Prevention of bronchospasm attacks associated with exposure to an allergen or caused by physical exertion;
– Use as a component of long-term maintenance therapy of bronchial asthma.
2. Chronic obstructive pulmonary disease (COPD) accompanied by reversible airway obstruction, chronic bronchitis.
Active ingredient
Salbutamol
Composition
Composition per 1 dose:
Active ingredient: | |
Salbutamol sulfate (in terms of salbutamol) | 0.120 mg (0.100 mg) | Excipients: |
Ethanol (ethyl alcohol absolute) | 5.905 mg |
Oleic acid | 0.009 mg |
Propellant R 134a (1,1,1,2-tetrafluoroethane) | 67.966 mg |
How to take, the dosage
Salbutamol aerosol for inhalation dosed 100 µg/dose is intended for inhalation administration only.
Interaction
It is not recommended to use salbutamol and non-selective ß-adrenoreceptor blockers such as propranolol simultaneously.
Special Instructions
Patients should be instructed on the correct use of Salbutamol. Correct use of the drug and clear compliance with the instructions are necessary to ensure that salbutamol enters the bronchi. At the beginning of treatment the drug should be used under the supervision of medical personnel and after training in front of a mirror.
Contraindications
- Hypersensitivity to the active ingredient or any other component of the drug.
- Preterm birth.
- Threatened abortion.
- Children under 2 years of age.
Cautions
Salbutamol Pharmstandard should be used with caution in patients with thyrotoxicosis, tachyarrhythmia, myocarditis, heart defects, aortic stenosis, coronary heart disease, severe chronic heart failure, arterial hypertension, pheochromocytoma, decompensated diabetes, glaucoma, and in pregnancy and during breastfeeding.
Side effects
In terms of frequency, side effects can be divided into the following categories: very frequently (>1/10), frequently (>1/100 and <1/10), infrequently (>1/1000 and <1/100), rarely (>1/10,000 and <1/100), very rarely (<1/10,000) occur.
Overdose
Symptoms of overdose: more frequent – hypokalemia, decreased blood pressure, tachycardia, muscle tremor, nausea, vomiting; less frequent – agitation, hyperglycemia, respiratory alkalosis, hypoxemia, headache; rare – hallucinations, seizures, tachyarrhythmia, ventricular flutter, dilation of peripheral vessels.
Pregnancy use
Pregnant women may be prescribed salbutamol only when the expected benefit to the patient exceeds the potential risk to the fetus.
Similarities
Salbutamol, Salbutamol-MCFP, Salbutamol-Pharmstandart, Novatron
Weight | 0.047 kg |
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Shelf life | 2 years. Do not use after the expiration date. |
Conditions of storage | Store at a temperature not exceeding 25°C. |
Manufacturer | Pharmstandard-Leksredstva, Russia |
Medication form | metered aerosol for inhalation |
Brand | Pharmstandard-Leksredstva |
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