Salbutamol-Pharmstandart, aerosol 100 mcg/dose 200 doses

Salbutamol is a selective β₂-adrenoreceptor agonist (β₂-adrenomimetic). In therapeutic doses it acts on β₂-adrenoreceptors of bronchial smooth muscle, having little or no effect on β₁-adrenoreceptors of the myocardium.

It has a pronounced bronchodilator effect, preventing or arresting bronchial spasm, reduces resistance in the airways. Increases the vital capacity of the lungs. Increases mucociliary clearance (in chronic bronchitis up to 36%), stimulates mucus secretion, activates the functions of the intermittent epithelium.

In recommended therapeutic doses does not have adverse effects on the cardiovascular system, does not cause an increase in blood pressure. To a lesser extent compared to the drugs of this group, it has positive chrono- and inotropic effects. It causes dilation of the coronary arteries.

It has a number of metabolic effects: it reduces the concentration of potassium in the blood plasma, affects glycogenolysis and insulin release, has hyperglycemic (especially in patients with bronchial asthma) and lipolytic effects, increases the risk of acidosis.

After using an inhaled dose of salbutamol, the action develops quickly, the beginning of the effect – in 5 minutes, the maximum effect – in 30-90 minutes (75% of the maximum effect is reached within 5 minutes), duration – 4-6 hours.

Indications

1. Bronchial asthma:

– control of bronchial asthma attacks, including severe bronchial asthma exacerbations;

– Prevention of bronchospasm attacks associated with exposure to an allergen or caused by physical exertion;

– Use as a component of long-term maintenance therapy of bronchial asthma.

2. Chronic obstructive pulmonary disease (COPD) accompanied by reversible airway obstruction, chronic bronchitis.

Active ingredient

Composition

Composition per 1 dose:

Active ingredient:

Salbutamol sulfate

(in terms of salbutamol)

0.120 mg

(0.100 mg)

Excipients:

Ethanol (ethyl alcohol absolute)

5.905 mg

Oleic acid

0.009 mg

Propellant R 134a (1,1,1,2-tetrafluoroethane)

67.966 mg

How to take, the dosage

Interaction

Special Instructions

Contraindications

Cautions

Salbutamol Pharmstandard should be used with caution in patients with thyrotoxicosis, tachyarrhythmia, myocarditis, heart defects, aortic stenosis, coronary heart disease, severe chronic heart failure, arterial hypertension, pheochromocytoma, decompensated diabetes, glaucoma, and in pregnancy and during breastfeeding.

Side effects

Overdose

Pregnancy use

Similarities