Sab Simplex, 69.19mg/ml 30 ml

Sub simplex, by reducing the surface tension at the interface, impedes the formation and promotes the destruction of gas bubbles in the intestinal contents. The gases released during this process can be absorbed by the intestinal walls or expelled through peristalsis. In sono- and radiography it prevents interference and overlapping of images; it promotes better irrigation of mucous coat of large intestine with contrast agent, preventing rupture of contrast film.

The simethicone changes the surface tension of gas bubbles that form in the stomach contents and intestinal mucus and causes their destruction. The released gases are absorbed by the intestinal wall or removed during intestinal peristalsis. Simethicone removes the foam physically and does not react chemically.

Pharmacokinetics

Due to physical and chemical inertness, it is not absorbed in the body, after passing through the gastrointestinal tract is eliminated unchanged.

Indications

Used as symptomatic therapy for increased gas formation, flatulence (including in the postoperative period);
preparation for diagnostic studies of the gastrointestinal tract (radiography, ultrasound, esophagogastroduodenoscopy);
acute poisoning from detergents containing surfactants when they enter the stomach.

Pharmacological effect

Sub simplex, by reducing the surface tension at the interface, impedes the formation and promotes the destruction of gas bubbles in the intestinal contents. The gases released during this process can be absorbed by the intestinal walls or excreted through peristalsis. Prevents interference and overlap of images during sonography and radiography; promotes better irrigation of the colon mucosa with a contrast agent, preventing rupture of the contrast film.

Simethicone changes the surface tension of gas bubbles formed in the contents of the stomach and intestinal mucus and causes their destruction. The released gases are absorbed by the intestinal wall or removed by intestinal peristalsis. Simethicone removes foam physically and does not enter into chemical reactions.

Pharmacokinetics

Due to physical and chemical inertness, it is not absorbed by the body; after passing through the gastrointestinal tract, it is excreted unchanged.

Special instructions

The drug Sab Simplex can be used, including in patients with diabetes, because does not contain carbohydrates.
New and/or recurring complaints associated with increased gas formation must be clinically confirmed.

Impact on the ability to drive a car and use equipment

Does not affect the ability to drive a car or operate machinery.

Active ingredient

Simethicone

Composition

100 ml of oral suspension contains:

active ingredient:

simethicone 6.919 g (dimethicone 350: silicon dioxide, in the ratio of 92.5%: 7.5%)

excipients:

hypromellose 1.5 g,

carbomer 0.6 g,

sodium citrate dihydrate 1.0 g,

citric acid monohydrate 0.5468 g,

vanilla flavoring 0.315 g,

raspberry flavor 0.108 g,

sodium cyclamate 0.2 g,

sodium saccharinate 0.02 g,

sodium benzoate 0.1 g,

polyglycostearyl acid esters 1.0378 g,

sorbic acid 0.0347 g,

water 89.6189 g

Contraindications

Hypersensitivity to the active substance simethicone or to any of the auxiliary components of the drug Sab Simplex,
obstructive diseases of the gastrointestinal tract,
intestinal obstruction.

Side Effects

Allergic reactions.

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

3 years

Manufacturer

Delpharm Orleans, France