Rosuvastatin-Vertex, 20 mg 30 pcs
€23.05 €19.97
Rosuvastatin is a selective competitive inhibitor of HMG-CoA reductase – an enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A into mevalonic acid, a precursor of cholesterol.
Indications
Primary Fredrickson hypercholesterolemia (type IIa, including familial heterozygous hypercholesterolemia) or mixed hypercholesterolemia (type IIb) as a dietary supplement, when diet and other non-drug treatments (e.g., exercise, weight loss) are not sufficient;
Active ingredient
Rosuvastatin
Composition
Filmed film-coated, light pink to pink, round, biconvex;
Interaction
Inhibitors of transport proteins: Rosuvastatin binds to some transport proteins, in particular to OATP1B1 and BCRP. Concomitant use of drugs that are inhibitors of these transport proteins may be accompanied by increased plasma concentrations of rosuvastatin and an increased risk of myopathy.
Directions for use
Orally, do not chew or crush the tablet, swallow it whole with water.
Special Instructions
Impaired renal function. In patients receiving high doses of rosuvastatin (in particular, 40 mg/day), tubular proteinuria has been observed, which was detected with the help of test strips and in most cases was intermittent or transient. Such proteinuria is not indicative of acute disease or progression of concomitant renal disease.
Contraindications
Daily dose up to 30 mg: hypersensitivity to rosuvastatin; liver disease in active phase (including persistent increase in hepatic transaminase activity and increase in serum hepatic transaminase activity by more than 3-fold compared to IGN); severe renal failure (creatinine Cl Daily dose 30 mg or more: hypersensitivity to rosuvastatin;
Side effects
Side effects observed with rosuvastatin are usually insignificant and go away on their own. As with other HMG-CoA reductase inhibitors, the incidence of side effects is mainly dose-dependent.
Overdose
Symptoms: the clinical picture of overdose is not described.
Pregnancy use
Rosuvastatin is contraindicated in pregnancy and lactation. Women of reproductive age should use adequate contraceptive methods.
Similarities
Mertenil, Crestor, Rosulip, Rosucard, Rosart, Rosuvastatin, Rosistarque, Roxera, Suvardio, Rosuvastatin NW, Cardiolip
Weight | 0.020 kg |
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Shelf life | 2 years |
Conditions of storage | Store in a dark place at a temperature not exceeding 25 ° C. |
Manufacturer | Vertex, Russia |
Medication form | pills |
Brand | Vertex |
Other forms…
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