Rosuvastatin-Vertex, 10 mg 90 pcs

Rosuvastatin is a selective competitive inhibitor of HMG-CoA reductase – an enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A into mevalonic acid, a cholesterol precursor. The main target of rosuvastatin action is the liver, where the synthesis of cholesterol (Chs) and catabolism of low-density lipoprotein cholesterol (LDL-C) take place.

Rosuvastatin increases the number of X-LDL receptors on the surface of liver cells, increasing the capture and catabolism of X-LDL, which in turn leads to the inhibition of synthesis of very low density lipoprotein cholesterol (X-LDL), thereby reducing the total amount of X-LDL and X-LDL.

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