Rosinsulin C, 100 me/ml suspension 3 ml cartridges 5 pcs

Special Instructions

Check the appearance of the contents of the vial carefully before each use and DO NOT USE Rosinsulin C if the suspension contains flakes after shaking or if particles of white have adhered to the bottom or walls of the vial, creating a frosty pattern.

Persistent Rosinsulin C should not be used if the suspension does not turn white and uniformly turbid after shaking.

With insulin therapy, continuous monitoring of blood glucose levels is necessary.

The causes of hypoglycemia in addition to insulin overdose may be: changing the drug, skipping meals, vomiting, diarrhea, increased physical activity, diseases that reduce the need for insulin (liver and kidney function disorders, adrenal, pituitary or thyroid hypofunction), change of injection site, and interaction with other medications.

Inadequate dosing or intermittent insulin administration, especially in patients with Type I diabetes, can lead to hyperglycemia. Usually the first symptoms of hyperglycemia develop gradually over a few hours or days. They include the appearance of thirst, increased frequency of urination, nausea, vomiting, dizziness, red and dry skin, dry mouth, loss of appetite, and the smell of acetone in the exhaled air. If left untreated, hyperglycemia in type 1 diabetes can lead to life-threatening diabetic ketoacidosis.

The insulin dose should be adjusted for thyroid dysfunction, Addison’s disease, hypopituitarism, hepatic and renal dysfunction, and diabetes mellitus in individuals over age 65.

The insulin dose may also need to be adjusted if the patient increases physical activity or changes their diet.

Concomitant diseases, especially infections and conditions with fever, increase the need for insulin.

Transition from one type of insulin to another should be done under control of blood glucose levels.

The drug reduces alcohol tolerance.

Due to the potential for precipitation in some catheters, use of the drug in insulin pumps is not recommended.

Contraindications

– Hypersensitivity to insulin or any of the ingredients of the drug;

– Hypoglycemia.

Side effects

Associated effects on carbohydrate metabolism: hypoglycemic states (pale skin, increased sweating, palpitations, tremors, hunger, agitation, paresthesias in the mouth, headache). Severe hypoglycemia may lead to hypoglycemic coma.

Allergic reactions: rare – skin rash, Quincke’s edema; very rare – anaphylactic shock.

Local reactions: hyperemia, swelling and itching at the injection site; with long-term use – lipodystrophy at the injection site.

Others: edema, transient refractive disorders (usually at the beginning of therapy).

Overdose

Hypoglycemia may occur in overdose.

Treatment: Mild hypoglycemia can be treated by the patient himself by taking sugar or carbohydrate-rich foods. Therefore, it is recommended that diabetics carry sugar, sweets, cookies, or sweet fruit juice with them at all times.

In severe cases, if the patient loses consciousness, a 40% solution of dextrose is administered intravenously; intramuscularly, subcutaneously, intravenously – glucagon. After recovery of consciousness, the patient is advised to take a meal rich in carbohydrates to prevent recurrence of hypoglycemia.