Riboxin, 200 mg 50 pcs

Riboxin is a derivative (nucleoside) of purine – the precursor of adenosine phosphate ATP. It belongs to the group of drugs that stimulate metabolic processes.

It has antihypoxic and antiarrhythmic effects. Increases myocardial energy balance, improves coronary circulation, prevents the consequences of intraoperative ischemia. It directly participates in glucose metabolism and promotes metabolism in hypoxia and in the absence of ATP.

Activates pyruvic acid metabolism to ensure the normal process of tissue respiration and also promotes activation of xanthine dehydrogenase.

Stimulates the synthesis of nucleotides and increases the activity of some enzymes of the Krebs cycle. By penetrating into cells, it has a positive effect on metabolic processes in the myocardium – it increases the force of heart contractions and promotes fuller myocardial relaxation in diastole, resulting in increased stroke volume.

The mechanism of antiarrhythmic action is not fully understood.

Limits platelet aggregation, activates tissue regeneration (especially myocardium and gastrointestinal mucosa).

Indications

Liver cirrhosisRiboxin is prescribed for adults in complex therapy of ischemic heart disease, myocardiodystrophy, after myocardial infarction, heart rhythm disorders caused by the use of cardiac glycosides. Prescribed for hepatitis, cirrhosis, fatty liver dystrophy caused by alcohol or drugs, and urocoproporphyria.

Active ingredient

Inosin

Composition

Active ingredient: inosine (Riboxin) – 200 mg in terms of 100% of substance.
Excipients: sucrose (refined sugar) -16.3 mg, calcium stearate monohydrate – 2.72 mg, gelatin – 3.26 mg, potato starch – 49.72 mg.

How to take, the dosage

Orally before meals. Maximum daily dose of the drug during oral administration is 0.6 – 2.4 g. During the first days of treatment the daily dose is 0.6 – 0.8 g (0.2 g 3 – 4 times a day). If the drug is well tolerated, the dose is increased during 2-3 days to 1.2 g (0.4 g three times a day), if necessary – up to 2.4 g a day.
Duration of the course is from 4 weeks to 1.5-3 months.
In case of urocoproporphyria daily dose is 0.8 g (0.2 g 4 times a day).
The drug is taken daily during 1-3 months.

Interaction

When used as part of a complex therapy Riboxin increases the effectiveness of antiarrhythmic, antianginal and inotropic drugs.

Special Instructions

Riboxin is not used for emergency correction of cardiac abnormalities.

Contraindications

Hypersensitivity to the drug, gout, hyperuricemia.
With caution
Renal failure.

Side effects

Allergic reactions: skin itching, skin hyperemia (the drug should be discontinued). Rare: increase of uric acid concentration in blood, exacerbation of gout (with long-term use).

Similarities

Riboxin Bufus, Riboxin-Solofarm