Riboxin, 200 mg 50 pcs

Riboxin is a derivative (nucleoside) of purine, a precursor of adenosine phosphate ATP. It belongs to the group of drugs that stimulate metabolic processes. It has antihypoxic and antiarrhythmic effects. It increases myocardial energy balance, improves coronary circulation, prevents the consequences of intraoperative renal ischemia. It directly participates in glucose metabolism and promotes metabolism in hypoxia and in the absence of ATP.

Activates pyruvic acid metabolism to ensure normal tissue respiration, and also helps activation of xanthine dehydrogenase. It stimulates the synthesis of nucleotides and enhances the activity of some Krebs cycle enzymes. By penetrating into cells, it has a positive effect on metabolic processes in the myocardium – it increases the force of heart contractions and promotes fuller myocardial relaxation in diastole, resulting in an increase in stroke volume. The mechanism of antiarrhythmic action is not fully understood.

Limits platelet aggregation, activates tissue regeneration (especially myocardium and gastrointestinal mucosa).

Pharmacokinetics

Metabolized in the liver with the formation of glucuronic acid and its subsequent oxidation. A small amount is excreted in the urine.

Indications

Complex treatment of myocardial infarction, ischemic heart disease, heart rhythm disorders caused by the use of cardiac glycosides, against myocardiodystrophy after infectious diseases.

Liver diseases (hepatitis, cirrhosis, fatty dystrophy). Surgery on the isolated kidney (as a means of pharmacological protection when the circulation is switched off).

Active ingredient

Composition

How to take, the dosage

Contraindications

Hypersensitivity to the drug, gout, hyperuricemia, pregnancy, lactation, age under 18 years (effectiveness and safety has not been established). Use with caution in renal failure.

Side effects

Allergic reactions: skin itching, skin hyperemia (the drug should be discontinued). Rare: increase of uric acid concentration in blood, exacerbation of gout (with long-term use).

Similarities