Ribomunil, bags 0.75, 4 pcs.
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Ribomunil has an immunomodulatory effect.
Pharmacodynamics
Ribosomal-proteoglycan complex of the most common pathogens of ENT-organ and respiratory tract infections, refers to stimulators of specific and non-specific immunity. Ribosomes contained in it contain antigens identical to the surface antigens of bacteria and when entering the body cause formation of specific antibodies to these pathogens (vaccine effect).
Membrane proteoglycans stimulate non-specific immunity, which is manifested by intensification of phagocytic activity of macrophages and polynuclear leukocytes and increase of non-specific resistance factors. The preparation stimulates function of T- and B-lymphocytes, production of serum and secretory immunoglobulins of IgA and IL-1 type and also alpha- and gamma- interferon.
This explains the prophylactic immunity of Ribomunil against respiratory viral infections. Application of Ribomunil in complex therapy allows to increase efficacy and shorten duration of treatment, considerably decrease necessity of antibiotics and bronchodilators application and extend remission period.
There are no data on pharmacokinetics of Ribomunil.
Indications
Prevention and/or treatment of recurrent ENT infections (otitis, sinusitis, rhinitis, pharyngitis, laryngitis, angina) and respiratory tract (chronic bronchitis, tracheitis, pneumonia, infection-dependent bronchial asthma) in patients over 6 months; prophylaxis of recurrent infections in risk groups of patients (frequently and long-time ill, before the beginning of the autumn-winter season, especially in environmentally disadvantaged regions, in patients with chronic diseases of ENT organs, chronic bronchitis, bronchial asthma, incl.including in children from 6 months of age and elderly patients).
Active ingredient
Composition
1 package (1 dose) contains:
Bacterial ribosomes titrated to 70% ribonucleic acid – 750 µg,
(including Klebsiella pneumoniae ribosomes – 3.5 fractions, Streptococcus pneumoniae – 3.0 fractions, Streptococcus pyogenes – 3.0 lobes, Haemophilus influenzae – 0.5 lobes);
Membrane proteoglycans
Klebsiella pneumoniae – 1.125 mg;
other components:
polyvidone,
D-mannite.
How to take, the dosage
Orally (adults and children over 6 months), once a day, in the morning, on an empty stomach.
A single dose (regardless of age) is 1 sachet pellets pre-dissolved with boiled water at room temperature.
In the first month of treatment and/or for preventive purposes Ribomunil is taken daily 4 days a week for 3 weeks, in the next 5 months – the first 4 days of each month.
In young children it is recommended to use granules.
Interaction
To date, no clinically significant drug interactions of Ribomunil have been described.
The use of the drug can be combined with other medicinal products.
Special Instructions
Patients should be warned about the possibility of transient increase in body temperature for 2-3 days, which is a manifestation of the therapeutic effect of the drug and does not usually require discontinuation of treatment.
The fever is sometimes accompanied by minor and transient symptoms of ENT infections.
Contraindications
Hypersensitivity; autoimmune diseases.
Side effects
It rarely occurs, characterized by the following conditions:
Overdose
There have been no reported cases of Ribomunil overdose at this time.
Pregnancy use
Special studies of safety and efficacy of Ribomunil during pregnancy and lactation have not been performed.
The use of Ribomunil during pregnancy and lactation (breastfeeding) is possible only after evaluation of the estimated benefit to the mother and the potential risk to the fetus and child.
Weight | 0.010 kg |
---|---|
Shelf life | 3 years. |
Conditions of storage | The drug should be kept out of reach of children and transported (by all types of roofed transport) at temperatures between 15° and 25°C. |
Manufacturer | Pierre Fabre Medical Production, France |
Medication form | oral solution |
Brand | Pierre Fabre Medical Production |
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