Rhinostop, drops 0.05% 10 ml

Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity, causes narrowing of blood vessels of nasal mucosa, thus eliminating edema and hyperemia of nasal mucosa, restores nasal passageways patency, facilitates nasal breathing.

The drug takes effect within a few minutes after application and lasts up to 10 hours.

Pharmacokinetics

The drug is practically not absorbed when applied topically, so its concentration in the blood plasma is very low (not determined by modern analytical methods).

Indications

It is used in acute respiratory diseases with rhinitis (runny nose), acute allergic rhinitis, sinusitis, otitis media (as part of combined therapy to reduce nasopharyngeal mucosa edema), runny nose in allergies and colds.

Preparing the patient for diagnostic manipulations in the nasal passages.

Active ingredient

Composition

1 ml of drops contains:

The active ingredient:

xylometazoline (as hydrochloride) 0.0005 g;

Associates:

benzalkonium chloride;

dinatrium salt of ethylenediaminetetetraacetic acid (trilon B);

Single displacement potassium phosphate;

divalent sodium phosphate;

sodium chloride;

purified water.

How to take, the dosage

It is used topically for 7-14 days.

The dose depends on the dosage form used and the age of the patient.

Contraindications

Hypersensitivity to xylometazoline and other components of the drug, arterial hypertension, tachycardia, marked atherosclerosis, glaucoma, atrophic rhinitis, brain surgery (in anamnesis), conditions after transsphenoidal hypophysectomy, children (under 2 years for 0.05% spray, under 6 years for 0.1% spray), pregnancy.

Do not use during therapy with monoamine oxidase inhibitors and tricyclic antidepressants (including the period of 14 days after their withdrawal).

Side effects

In frequent and/or prolonged use: mucosal irritation, burning, tingling, sneezing, dry nasal mucosa, hypersecretion.

Rarely: nasal mucous membrane swelling (more common with long-term use), palpitations, heart rhythm disorders, increased BP, headache, vomiting, sleep disorders, visual disturbances.

In long-term use in high doses: depression.

Pregnancy use

In pregnancy and during lactation Rinostop should be used only after careful assessment of the risk-benefit ratio for the mother and fetus, the recommended doses should not be exceeded.

Similarities