Reafferon EU Lipint is an antiviral and immunomodulatory drug, which is human recombinant interferon alpha-2b encapsulated in liposomes and lyophilically dried.
Indications
Complex therapy for patients with acute hepatitis B, chronic hepatitis B in active and inactive replicative forms, as well as chronic hepatitis B complicated by glomerulonephritis.
Treatment of patients with atopic diseases, allergic rhinoconjunctivitis, bronchial asthma during specific immunotherapy.
Prevention and treatment of influenza and ARVI in adults and children.
Complex therapy of urogenital chlamydial infection in adults.
Complex therapy of febrile and meningeal forms of tick-borne encephalitis in adults.
Emergency prevention of tick-borne encephalitis in combination with anti-tick immunoglobulin.
Pharmacological effect
Reaferon EC Lipint is an antiviral and immunomodulatory drug, is a human recombinant interferon alpha-2b, enclosed in liposomes and freeze-dried.
Special instructions
A solution of the drug Reaferon-ES-Lipint should be prepared immediately before use.
During treatment with Reaferon-ES-Lipint, systematic monitoring of bone marrow, liver, and kidney function is required, as well as regular neurological examination of patients.
Reaferon-EC-Lipint is effective for fever and headaches.
Active ingredient
Interferon alpha-2b
Composition
One bottle contains: 1 million IU of human recombinant Interferon alpha-2b; excipients: sodium chloride – 8.01 mg, sodium hydrogen phosphate dodecahydrate – 4.52 mg, sodium dihydrogen phosphate dihydrate – 0.56 mg, Lipoid C 100 (phospholipids [mixture with a percentage of phosphatidylcholine of at least 94%]) – 41.18 mg, cholesterol – 4.53 mg, alpha-tocopherol acetate – 0.56 mg, lactose monohydrate – 91.34 mg.
Pregnancy
Reaferon-ES-Lipint is contraindicated during pregnancy, lactation and children under 2 years of age.
Contraindications
hypersensitivity to the drug Reaferon-ES-Lipint;
severe liver or kidney dysfunction;
severe cardiovascular diseases;
epilepsy.
Side Effects
When used according to indications in recommended doses, the drug has no side effects.
However, given that its active ingredient is recombinant interferon, which causes flu-like side effects when administered parenterally, caution is required when prescribing the drug to persons with individual intolerance to interferon preparations.
flu-like condition;
nausea, vomiting, diarrhea;
“crawling” sensation, trembling of limbs;
blood picture disturbance;
liver dysfunction;
dizziness, drowsiness;
decrease or increase in blood pressure, arrhythmias.
Interaction
Interferon alpha-2b is able to reduce the activity of cytochrome P450 isoenzymes and, therefore, when used simultaneously, affect the metabolism of cimetidine, phenytoin, dipyridamole, theophylline, diazepam, propranolol, warfarin, and some cytostatics.
The drug may enhance the neurotoxic, myelotoxic or cardiotoxic effects of drugs prescribed previously or simultaneously with it.
Storage conditions
In a place protected from light, at a temperature not exceeding 8 °C
Shelf life
2 years
Manufacturer
Vector-Medica JSC, Russia
Shelf life | 2 years |
---|---|
Conditions of storage | In a light-protected place, at a temperature not exceeding 8 °C |
Manufacturer | Vector-Medica JSC, Russia |
Medication form | lyophilizate |
Brand | Vector-Medica JSC |
Other forms…
Related products
Buy Reafferon-ES-Lipint, lyophilizate 1000000 me 5 pcs with delivery to USA, UK, Europe and over 120 other countries.