Potassium orotate, tablets 500 mg 20 pcs

Potassium orotate has an anabolic and regenerating effect.

It is one of the precursors of pyrimidine nucleotides (uracil, thymine, cytosine), which are components of nucleic acids that participate in the synthesis of proteins.

It is used as a regenerant in disorders of protein metabolism and as a stimulant of metabolic processes.

It enhances reparative and regenerative processes in tissues, increases formation of albumin in the liver, especially in conditions of prolonged hypoxia in some diseases, such as in heart failure.

Potassium orotate is involved in carbohydrate and lipid metabolism. The participation of orotic acid in carbohydrate metabolism is its effect on the metabolism of galactose.

Potassium orotate helps to increase diuresis (has diuretic effect).

Enhances appetite. Improves tolerance of cardiac glycosides.

Indications

Potassium orotate is used in complex therapy in combination with other medications (vitamins, cardiotonic drugs, etc.):
– diseases of the liver and biliary tract as a result of acute or chronic intoxication (except for cirrhosis of the liver with ascites);
– myocardial dystrophy (myocardial dystrophy), myocardial infarction and chronic heart failure stages II and III (as part of combination therapy);
– malnutrition, dystrophy in children (nutritional and nutritional-infectious);
– anemia;
– progressive muscular dystrophy;
– period of convalescence after illnesses;
– heart rhythm disturbances (especially extrasystole and atrial fibrillation; the effect of potassium orotate is explained in these cases by the presence of potassium ion in the preparation);
– increased physical activity;
– for other indications, when it is advisable to stimulate anabolic processes.

Pharmacological effect

Potassium orotate has an anabolic and regenerating effect.

It is one of the precursors of pyrimidine nucleotides (uracil, thymine, cytosine), which are part of nucleic acids that are involved in protein synthesis.

It is used as a regenerant for protein metabolism disorders, as a stimulator of metabolic processes.

Enhances reparative and regenerative processes in tissues, enhances the formation of albumin in the liver, especially under conditions of prolonged hypoxia, which occurs in certain diseases, for example, heart failure.

Potassium orotate is involved in carbohydrate and lipid metabolism. The participation of orotic acid in carbohydrate metabolism lies in its effect on galactose metabolism.

Potassium orotate helps increase diuresis (has a diuretic effect).

Increases appetite. Improves the tolerance of cardiac glycosides.

Special instructions

A combination of orotic acid and magnesium (magnesium orotate) is promising for use in cardiological practice.

Potassium orotate should not be used as a potassium-containing drug for potassium replacement therapy.

Active ingredient

Orotic acid

Composition

Pills.

1 tablet contains:

orotic acid (in the form of potassium salt) 500 mg.

Contraindications

– cirrhosis of the liver with ascites;
– individual intolerance (including a history of hypersensitivity) to orotic acid or its salts.
Potassium orotate is used with caution:
– renal failure;
– pregnancy and lactation period.

Side Effects

Potassium orotate is generally well tolerated.

In some cases, allergic reactions (dermatoses) are observed, which quickly disappear after discontinuation of Potassium Orotate.

If necessary, antihistamines are prescribed. Dyspeptic symptoms are possible.

Potassium orotate in high doses can cause liver dystrophy on a low-protein diet.

If side effects occur, consult your doctor.

Interaction

Potassium orotate slightly reduces the toxicity and improves the tolerability of cardiac glycosides (digoxin, celanide, etc.).

Astringents and enveloping agents (de-nol, sucralfate, algeldrate and magnesium hydroxide, etc.) may slightly reduce the absorption of potassium orotate in the gastrointestinal tract.

The effectiveness of Potassium orotate increases with the combined administration of folic acid and cyanocobalamin.

Storage conditions

In a dry place, out of reach of children, at a temperature not exceeding 25°C.

Shelf life

4 years.

Manufacturer

ABVA RUS, Russia