Polyvalent piobacteriophage (Sextaphage), 20 ml 4 pcs

Polyvalent piobacteriophage is immunostimulatory.

Lysis of microorganisms corresponding to the phage (staphylococci, streptococci, pathogenic intestinal and Pseudomonas bacteria), Proteus (mirabilis, vulgaris, Klebsiella pneumoniae).

Indications

treatment and prevention of purulent-inflammatory and enteric diseases caused by staphylococci, streptococci, Proteus, Klebsiella, Pseudomonas aeruginosa and Escherichia coli:

– diseases of the ear, throat, nose, respiratory tract and lungs – inflammation of the sinuses, middle ear, sore throat, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleurisy;

-surgical infections – wound suppuration, burns, abscess, phlegmon, boils, carbuncles, hydroadenitis, panaritium, paraproctitis, mastitis, bursitis, osteomyelitis;

-urogenital infections – urethritis, cystitis, pyelonephritis, colpitis, endometritis, salpingoophoritis;

– post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcers and iridocyclitis;

-enteric infections – gastroenterocolitis, cholecystitis, dysbacteriosis;

-generalized septic diseases;

– purulent-inflammatory diseases of newborns – omphalitis, pyoderma, conjunctivitis, gastroenterocolitis, sepsis, etc.;

– other diseases caused by bacteria of staphylococci, streptococci (including enterococci), Proteus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli.

For severe manifestations of infections caused by staphylococci, streptococci, Proteus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli, the drug is prescribed as part of complex therapy.

For prophylactic purposes, the drug is used for the treatment of surgical and newly infected wounds, as well as for the prevention of nosocomial infections for epidemic indications.

An important condition for effective phage therapy is the preliminary determination of the phage sensitivity of the pathogen.

Pharmacological effect

Pharmacotherapeutic group. Absent.

ATX code. V03A.

Pharmacological properties. The drug has the ability to specifically lyse bacteria of staphylococci, streptococci (including enterococci), Proteus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli.

Special instructions

An important condition for effective phage therapy is the preliminary determination of the sensitivity of the pathogen to the bacteriophage and the early use of the drug.

The drug is not suitable for use in bottles with damaged integrity or labeling, if the expiration date has expired, or if they are cloudy.

Before use, the bottle with liquid bacteriophage must be shaken. If there is turbidity, do not use the drug!

Due to the content of a nutrient medium in the drug, in which bacteria from the environment can develop, causing cloudiness of the drug, the following rules must be observed when opening the bottle:

– wash your hands thoroughly;

– treat the cap with an alcohol-containing solution;

– remove the cap without opening the cap;

– do not place the cork with the inner surface on a table or other objects;

-do not leave the bottle open;

– Store the opened bottle only in the refrigerator.

When using small doses (2-8 drops), the drug must be taken with a sterile syringe in a volume of 0.5-1 ml.

The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the shelf life.

Influence on the ability to drive vehicles and machinery. The drug does not affect the ability to perform potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (including driving vehicles, working with moving mechanisms).

Active ingredient

Pyobacteriophage

Composition

1 ml of the drug contains:

Active ingredient.

Sterile purified filtrates of phagolysates of bacteria Staphylococcus spp., Streptococcus spp., Proteus (P. vulgaris, P. mirabilis), Pseudomonas aeruginosa, Klebsiella pneumoniae, enteropathogenic Escherichia coli (with Appelman activity – at least 10-5) – up to 1 ml.

Excipient.

8-hydroxyquinoline sulfate monohydrate (preservative) in terms of 8-hydroxyquinoline sulfate – 0.0001 g/ml (calculated content).

Pregnancy

It is advisable to use the drug during pregnancy and breastfeeding in the presence of infections caused by phage-sensitive strains of bacteria (on the recommendation of a doctor).

Contraindications

None.

Side Effects

Allergic reactions are possible. If you experience side effects listed in the instructions or they get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

The drug can be used in combination with other drugs, including antibiotics.

Overdose

No cases of overdose have been reported to date.

Storage conditions

Transportation conditions. At temperatures from 2 to 8 °C, transportation is allowed at temperatures from 9 to 25 °C for no more than 1 month.
Storage conditions. At a temperature of 2 to 8 ° C in a place protected from light. Keep out of the reach of children.

Shelf life

2 years. Do not use after expiration date.

Manufacturer

Microgen NPO, Russia