Pirantel, suspension 250 mg/5 ml 15 ml

Name: Pirantel, suspension 250 mg/5 ml 15 ml
SKU: 200872
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EAN: 5907529412121 SKU: 200872 Categories: Medicine, Worms, Worms, lice, scabies

Description

Pirantel is an anthelmintic.

Blocks neuromuscular transmission in susceptible helminthes.

Pharmacodynamics

Acts on helminths in the early phase of development and mature forms, has no effect on larvae in the migration stage. It is active against Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Trichostrongylus orientalis, Trichostrongylus colubriformis.

Pharmacokinetics

It is practically not absorbed in the gastrointestinal tract. After oral administration at a single dose of 10 mg/kg body weight Cmax is 0.005-0.13 mcg/ml and is reached within 1-3 hours.

Partially metabolized in the liver to N-methyl-1,3-propanediamine. It is excreted in the faeces (50% of the taken dose – unchanged) and in the urine (about 7% – unchanged and as a metabolite).

Indications

Appetite disorders, Worms, Skin itching

Enterobiasis, ascariasis, ankylostomidiasis, necatoriasis.

Active ingredient

Pirantel

Composition

5 ml of the suspension contains:

The active ingredient:

pyrantel 250 mg;

Associates:

sorbic acid,

sucrose,

/p>

xanthan gum,

methylparahydroxybenzoate,

/p>

propyl parahydroxybenzoate,

sorbitol 70% solution,

polysorbate 80,

Chocolate flavoring S 2761 (composition: propylene glycol, water, caramel dye, natural, identical to natural and artificial fragrances),

“ice cream” flavoring (composition: propylene glycol, water, caramel dye, natural, identical to natural and artificial fragrances),

purified water.

How to take, the dosage
How to take, the dosage
In case of ascariasis and enterobiasis, in mixed infestations with these helminthes – orally, once, after breakfast at the rate of 10 mg/kg.
Adults and children over 12 years – 750 mg, if body weight over 75 kg – 1 g.
In children from 6 months to 2 years – 125 mg, 2 – 6 years – 250 mg, 6 – 12 years – 500 mg. In order to avoid self-infection it is allowed to repeat the course in 3 weeks after the first intake.
In case of ankylostomiasis, combined necatoriasis and ascariasis or other combined helminth infestations the dose is 10 mg/kg/day for 3 days or 20 mg/kg/day for 2 days.
In case of isolated ascariasis – 5 mg/kg once.

Interaction
Interaction
Should not be administered simultaneously with piperazine (weakening of action).
Pirantel increases the concentration of theophylline in plasma when used concomitantly.
.

Special Instructions
Special Instructions
No laxatives are prescribed after pyrantel administration.
In case of enterobiasis all persons living together should be treated at the same time. After completion of treatment it is necessary to conduct a control examination of feces for the presence of parasite eggs.
Careful hygiene (cleaning of living rooms and cleaning of clothing to destroy the helminth eggs serves as a prevention of reinfection).
.

Side effects
Side effects
Nervous system and sensory organs: rarely – headache, dizziness, drowsiness, insomnia, weakness; in some cases – hearing impairment, hallucinations, confusion, paresthesias.
Gastrointestinal system disorders: nausea, vomiting, diarrhea, stomach pain; rarely – increased liver transaminase activity.
Other: skin rash, fever.
.

Pregnancy use
Pregnancy use
Pregnancy and breast-feeding can be used only under the strict supervision of a doctor.
.

Additional information
Weight 0.071 kg
Shelf life
3 years
Conditions of storage
In a dry, light-protected place at a temperature below 25 °C
Manufacturer
Polpharma S.A., Poland
Medication form
oral suspension
Brand
Polpharma S.A.