Pentaflucin, 5 g 5 pcs

Pentaflucin is a combined medicine with antipyretic and anti-inflammatory effects. Its action is due to the constituent active ingredients:

• Paracetamol has antipyretic and analgesic effects. Non-narcotic analgesic, blocks COX1 and COX2 mainly in the CNS, affecting the centers of pain and thermoregulation. In inflamed tissues the cell peroxidase neutralizes the effect of paracetamol on COX, which explains the almost complete lack of anti-inflammatory effect.
• Ascorbic acid plays an important role in the regulation of redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration, increases the body’s resistance.
• Diphenhydramine has antihistamine and anti-inflammatory, sedative and hypnotic effect.
• Rutosine reduces capillary permeability and fragility, has antioxidant properties.
  

Indications

Hyperthermia for colds and other infectious and inflammatory diseases.

Pharmacological effect

Pentaflucin is a combination drug that has antipyretic and anti-inflammatory effects. Its action is due to the active ingredients included in its composition:

Paracetamol has an antipyretic and analgesic effect. A non-narcotic analgesic, it blocks COX1 and COX2 mainly in the central nervous system, affecting the centers of pain and thermoregulation. In inflamed tissues, cellular peroxidases neutralize the effect of paracetamol on COX, which explains the almost complete absence of anti-inflammatory effect.
Ascorbic acid plays an important role in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration, and increases the body’s resistance.
Diphenhydramine has antihistamine and anti-inflammatory, sedative and hypnotic effects.
Rutosin reduces the permeability and fragility of capillaries and has antioxidant properties.

Special instructions

The drug should not be combined with ethanol consumption to avoid toxic liver damage.

Impact on the ability to drive vehicles and operate machinery

During the treatment period, it is necessary to refrain from driving vehicles and engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Active ingredient

Paracetamol, Ascorbic acid, Rutoside, Diphenhydramine, Calcium gluconate

Composition

1 sachet contains

Active ingredients:

paracetamol 500 mg,
ascorbic acid 200 mg,
diphenhydramine 20 mg,
rutin 20 mg.

Pregnancy

Contraindicated: pregnancy and lactation.

Use in children.

Contraindicated: children under 16 years of age.

Contraindications

Hypersensitivity, renal and/or liver failure, blood diseases with a tendency to hemorrhage, glucose-6-phosphate dehydrogenase deficiency, pregnancy, lactation, children (up to 16 years).

Side Effects

Possible drowsiness and allergic skin reactions (rash, itching, urticaria), nausea, vomiting, headache, general weakness, dizziness.

Rarely – thrombocytopenia, leukopenia, agranulocytosis.

With long-term use in high doses, hepatotoxic and nephrotoxic effects are possible.

Interaction

Combination of the drug with barbiturates, anticonvulsants, diphenin, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes should be avoided.

Overdose

Symptoms: nausea, vomiting, stomach pain, after 1-2 days – liver failure, encephalopathy, coma.

Treatment: induce vomiting, gastric lavage, administration of adsorbents (activated carbon), symptomatic therapy (administration of methionine, acetylcysteine).

Storage conditions

In a dry place, protected from light

Shelf life

2 years

Manufacturer

Uralbiopharm, Russia