Otinum, ear drops 10 ml

Choline salicylate is a derivative of salicylic acid, when put into the ear has anti-inflammatory and anelgesic effect.

The action of choline salicylate is based on inhibition of cyclooxygenase activity – the enzyme responsible for the synthesis of prostaglandins. Choline salicylate also inhibits the synthesis of thromboxane and prostacyclin.

It also has antimicrobial and antifungal effects (in acidic and alkaline environments).

It has no systemic action when used topically.

Indications

Softening of hardened earwax before the procedure of its removal from the ear.

Active ingredient

Composition

1 g of the drug contains:

The active ingredient:

Choline salicylate – 0.200 g

Associates:

Interaction

There are no data indicating interactions between choline salicylate and other medications when it is put in the ear.

Directions for use

In acute and chronic otitis media, myringitis and otitis externa

Push into the external auditory canal 3-4 drops 3-4 times a day.

The course of treatment should not exceed 3 days.

To soften “wax plugs” before they are removed

Push 3-4 drops into the external auditory canal twice a day for 4 days.

We recommend that the bottle be warmed in the hand before using the ear drops to avoid discomfort caused by allowing cold fluid to get into the ear.

The drops should be placed into the ear while lying on its side with the ear pointing upward. After the procedure, the person needs to stay in the same position for a few minutes.

There is no need to change the dosing regimen for the elderly, children and patients with hepatic or renal impairment.

If there is no improvement after treatment, or if symptoms worsen or new symptoms develop, you should consult a physician. Use the drug only according to the indication, route of administration, and dosage listed in the directions for use.

Special Instructions

In children under 1 year of age, the drug should be used only under close medical supervision.

Salicylic acid derivatives can cause hearing loss or deafness if they enter the middle ear through a damaged eardrum. Because of this, the drug should not be used without prior examination by an otorhinolaryngologist and without a physician’s instruction.

The effect of the drug on the ability to drive vehicles, machinery

The drug does not affect the ability to drive vehicles or engage in other potentially dangerous activities requiring increased concentration and quick psychomotor reactions.

Synopsis

Features

There are no data on the pharmacokinetics of choline salicylate when injected into the ear.

Contraindications

Hypersensitivity to choline salicylate or other drug components.

The complete or incomplete combination of bronchial asthma, recurrent nasal and paranasal sinus polyposis and intolerance to acetylsalicylic acid or other NSAIDs (including history).

Disturbance of the integrity of the eardrum.

Pregnancy and breastfeeding (due to lack of data).

Children under 1 year of age.

With caution

Allergic (“hay”) runny nose, polyps of the nasal passages.

Side effects

Local hypersensitivity reactions: itching, skin redness.

Ear diseases: use of the drug in patients with perforated eardrums may lead to hearing impairment.

If you have any side effects mentioned in the directions, or if they get worse, or if you notice any other side effects not mentioned in the directions, tell your doctor.

Overdose

It is not possible to overdose when putting it in the ear.

One bottle of the drug contains 2 grams of choline salicylate. If accidentally swallowed, this amount can only be dangerous for infants.

Symptoms

The symptoms that can occur if an overdose is swallowed are confusion, dizziness, increased sweating, vomiting, tinnitus, and hyperventilation. After swallowing very large amounts of the drug, symptoms of CNS depression, such as drowsiness, lethargy, seizures, and coma may occur.

Treatment

Help for oral overdose:

– removal of choline salicylate from the body (induce vomiting, rinse the stomach, take activated charcoal);

– control of the patient’s condition (above all – water and electrolyte balance);

– symptomatic treatment (including correction of the water and electrolyte balance; in cases where the concentration of salicylate exceeds 300 mg per liter – forced diuresis).