Ornidazole-vero, 500 mg 10 pcs
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Antiprotozoal drug with antibacterial activity.
The mechanism of action of Ornidazole-Vero consists in biochemical reduction of the 5-nitrogroup of ornidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitrogroup of ornidazole interacts with the DNA of the microbial cell, inhibiting the synthesis of their nucleic acids, which leads to the death of the bacteria.
Ornidazole-Vero is active against Trichomonas vaginalis, Gardnerella vaginalis, Giardia intestinalis, Entamoeba histolytica; obligate anaerobic microorganisms: Bacteroides spp. (including Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp, Veillonela spp., Prevotella spp. (Prevotella bivia, Prevotella buccae, Prevotella disiens); Gram-positive microorganisms: Eubacterium spp.
Aerobic microorganisms are not sensitive to the drug.
Indications
Intestinal infections, Trichomoniasis, Amoebiasis and Giardiasis
- trichomoniasis;
- amoebiasis, amebic dysentery, extraintestinal amoebiasis (including.
- giardiasis;
- prevention of infections caused by anaerobic bacteria during colorectal and gynecological surgeries
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Active ingredient
Ornidazole
Composition
1 tablet contains ornidazole 500 mg, 10 pieces per pack.
How to take, the dosage
The tablets are taken orally after meals.
In case of trichomoniasis, adults are prescribed 500 mg 2 times a day for 5 days. In children the dose is established at the rate of 25 mg/kg of body weight once a day.
In case of amebic dysentery in adults and children with body weight over 35 kg 1.5 g 1 time per day, in those with body weight over 60 kg – 2 g/day. The daily dose for children with body weight less than 35 kg is 40 mg/kg of body weight. The course of treatment is 3 days.
In case of other forms of amoebiasis in adults and children with body weight over 35 kg – 500 mg twice a day, in children with body weight less than 35 kg – 25 mg/kg once a day for 5-10 days.
In case of giardiasis in adults and children with body mass of more than 35 kg – 1.5 g 1 time per day, in children with body mass less than 35 kg – 40 mg/kg/day The therapy duration is 1-2 days.
For prevention of postoperative infections caused by anaerobic bacteria, 500 mg and then 500 mg every 12 hours for 3-5 days.
Interaction
Drug interactions of the drug have not been described.
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Special Instructions
When treating trichomoniasis, both sexual partners should be treated simultaneously.
Contraindications
- organic CNS disorders
- Pregnancy first trimester
- lactation (breastfeeding) period
- high sensitivity to the drug components (including nitrodazole derivatives.
Side effects
CNS and peripheral nervous system disorders: headache, dizziness, impaired consciousness, tremor, rigidity, discoordination of movements, seizures, sensory or mixed peripheral neuropathy.
Digestive system disorders: nausea, vomiting, diarrhea.
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Overdose
Symptoms: epileptiform seizures, depression, peripheral neuritis.
Treatment: symptomatic therapy.
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Pregnancy use
In pregnancy and during lactation (breastfeeding) the use of the drug is contraindicated.
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Similarities
Tiberal, Dasolik, Ornidazole
Weight | 0.017 kg |
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Shelf life | 2 years. |
Conditions of storage | Store at a temperature not exceeding 25 ° C. |
Manufacturer | Veropharm AO, Russia |
Medication form | pills |
Brand | Veropharm AO |
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