Nurofen Express, gel 5% 50 g

Nurofen Express (ibuprofen) gel 5% is quickly absorbed, acting directly on the source of pain and has a double effect – analgesic and anti-inflammatory

The drug Nurofen Express in the form of gel for external use is easily applied and quickly absorbed into the skin.

Indications

Active ingredient

Composition

1 g of gel for external use 5% contains:

How to take, the dosage

Interaction

Special Instructions

Contraindications

Side effects

Overdose

Orally administering activated charcoal or gastric lavage within one hour of taking a potentially toxic dose of ibuprofen is recommended. If ibuprofen has already been absorbed, alkaline drinking may be prescribed in order to eliminate the acidic derivative of ibuprofen by the kidneys.

Frequent or prolonged seizures should be controlled with intravenous diazepam or lorazepam. In worsening bronchial asthma, the use of bronchodilators is recommended. In children, symptoms may occur after a dose greater than 400 mg/kg body weight.

The dose-dependent effect is less pronounced in adults. The half-life of the drug in overdose is 1.5 to 3 hours.

Symptoms: In most patients who have used clinically significant doses of NSAIDs, overdose symptoms are limited to nausea, vomiting, epigastric pain or, rarely, diarrhea.

Symptoms such as tinnitus, headache and gastrointestinal bleeding may occur. In more severe cases, manifestations of the central nervous system are observed, in particular, drowsiness, occasionally excitement, as well as disorientation or coma.

In rare cases, seizures occur. In cases of severe poisoning metabolic acidosis and increased prothrombin time may develop, which is probably associated with interactions of ibuprofen and circulating clotting factors. Acute renal failure, liver tissue damage, decreased BP, respiratory depression and cyanosis may occur. In patients with bronchial asthma exacerbation of this disease is possible.

Treatment: should be symptomatic and supportive, with mandatory provision of airway patency, ECG monitoring and basic vital signs until the patient’s condition normalizes.

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