Nootropil, 1200 mg 20 pcs

Notropil improves cognitive (learning) processes such as learning ability, memory, attention, and mental performance.

Notropil affects CNS in different ways: it changes the speed of excitation distribution in the brain, improves metabolic processes in nerve cells, improves microcirculation by affecting the rheological characteristics of blood without causing vasodilatation.

It improves connections between cerebral hemispheres and synaptic conduction in neocortical structures, increases mental performance, improves cerebral blood flow.

Inhibits platelet aggregation and restores erythrocyte membrane elasticity, reduces erythrocyte adhesion. At a dose of 9.6 g it decreases the level of fibrinogen and Willebrand factors by 30%-40% and prolongs the bleeding time.

Notropil has a protective and restorative effect in disorders of brain function due to hypoxia and intoxication.

Limits the severity and duration of vestibular nystagmus.

Indications

Active ingredient

Composition

Active ingredient:

piracetam 800 or 1200 mg;

Excipients:

macrogol 6000,

colloidal silicon anhydride (Aerosil R972),

magnesium stearate,

Croscarmellose sodium,

Titanium dioxide (E171),

Macrogol 400,

Hydroxypropyl methylcellulose

How to take, the dosage

Daily doses range from 30-160 mg/kg body weight. The frequency of administration is 2-4 times a day.

In treatment of chronic psychoorganic syndrome the drug is prescribed at a dose of 4.8 g/day for the first week and then changed to a maintenance dose of 1.2-2.4 g/day.

In the treatment of ischemic stroke, Nootropil should be given in a dose of 4.8 g/day.

When treating comatose states as well as perceptual difficulties in persons with brain injuries the initial dose is 9-12 g/day, maintenance dose is 2.4 g/day. Treatment should be continued for at least 3 weeks.

In case of withdrawal in chronic alcoholism the dose of the drug reaches 12 g/day during the manifestation of alcohol withdrawal syndrome. Maintenance dose is 2.4 g/day.

In treatment of dizziness and associated balance disorders the dose is 2.4-4.8 g/day.

In the correction of learning disabilities Nootropil is prescribed in a daily dose of 3.3 g (about 8 ml of 20% solution for oral administration 2 times a day). The treatment must continue throughout the school year.

In case of cortical myoclonias treatment is started with a dose of 7.2 g/day, every 3-4 days the dose is increased by 4.8 g/day until a maximum dose of 24 g/day is reached. Treatment with Nootropil is continued for the entire period of the disease. Every 6 months an attempt should be made to reduce the dose or cancel the drug, gradually reducing the dose by 1.2 g/day every 2 days. If there is no effect or little therapeutic effect, treatment should be discontinued.

In sickle cell anemia, the daily prophylactic dose is 160 mg/kg body weight divided into 4 doses. During a crisis, up to 300 mg/kg v/v. This dose can be administered to children over the age of 1 year.

The drug is administered orally with meals or on an empty stomach; tablets and capsules should be washed down with liquids (water, juice). Parenterally if oral administration is not possible, in the same daily dose.

Special Instructions

Caution should be exercised when prescribing the drug in patients with impaired hemostasis, during major surgery or in patients with symptoms of severe bleeding.

When treating patients with cortical myoclonias, abrupt withdrawal of therapy should be avoided since this may cause a recurrence of seizures.

In long-term therapy of elderly patients, regular monitoring of renal function parameters is recommended; if necessary, the dose should be adjusted depending on the results of creatinine clearance study.

Notropil passes through the filter membranes of hemodialysis machines.

Impact on driving and operating machinery

With due regard to possible adverse effects, the patient should use caution when operating machinery and driving.

Contraindications

Side effects

CNS side effects: hyperkinesia (1.72%), nervousness (1.13%), drowsiness (0.96%), depression (0.83%), asthenia (0.23%). These side effects occur more frequently in elderly patients who received the drug in a dose greater than 2.4 g/day.

In some cases – dizziness, headache, ataxia, loss of balance, worsening of the course of epilepsy, insomnia, confusion, agitation, anxiety, hallucinations, increased sexuality.

Metabolism: weight gain (1.29%).

Digestive system disorders: in some cases – nausea, vomiting, diarrhea, abdominal pain.

Dermatological reactions: dermatitis, itching, rash, edema.

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