Noopept, tablets 10 mg 50 pcs

Pharmacotherapeutic group: nootropic agent.

The ATX code: N06BX

Pharmacological properties

Pharmacodynamics

Noopept^® has nootropic and neuroprotective properties. Improves learning ability and memory by acting on all phases of processing: initial information processing, consolidation, retrieval. Prevents the development of amnesia caused by electroshock, blockade of central cholinergic structures, glutamatergic receptor systems, deprivation of the paroxysmal phase of sleep.

The neuroprotective (protective) effect of Noopept® is manifested by increasing resistance of brain tissue to damaging influences (trauma, hypoxia, electroconvulsive, toxic) and weakening of the degree of damage of brain neurons.

The drug reduces focal volume in a thrombotic model of stroke and prevents neuronal death in tissue culture of the cerebral cortex and cerebellum exposed to neurotoxic concentrations of glutamate and free-radical oxygen.

Noopept^® has antioxidant action, blocks potential-dependent calcium channels of neurons, attenuating the neurotoxic effects of excess calcium, improves blood rheological properties with antiaggregant, fibrinolytic, anticoagulant properties.

The nootropic effect of the drug is connected with the formation of cycloprolilglycine which is similar in structure to the endogenous cyclic dipeptide with antiamnestic activity, and also with the presence of choline-positive action.

Noopept^® increases the amplitude of the transcallosal response, facilitating associative connections between cerebral hemispheres at the level of cortical structures. Helps to restore memory and other cognitive functions impaired as a result of damaging influences – brain trauma, local and global ischemia, prenatal damage (alcohol, hypoxia).

The therapeutic effect of the drug in patients with organic disorders of the

the central nervous system is manifested starting from day 5-7 of treatment. At first the anxiolytic and mild stimulant effects available in the activity spectrum of Noopept® are realized, which are manifested by decrease or disappearance of anxiety, increased irritability, affective lability, sleep disturbances. After 14-20 days of therapy a positive effect of the drug on cognitive functions, attention and memory parameters is observed.

Noopept® has a vegetal-normalizing effect, reduces headaches, orthostatic disorders and tachycardia.

There is no withdrawal syndrome on withdrawal of the drug.

The drug does not cause any harmful effect on internal organs; it does not lead to changes in the cellular composition of blood and biochemical parameters of blood and urine; it has no immunotoxic, teratogenic effect and does not show mutagenic properties.

Pharmacokinetics

Omberacetam, absorbed in the gastrointestinal tract, enters the systemic bloodstream unchanged, penetrates through the blood-brain barrier and is determined in the brain in higher concentrations than in blood. Time to reach maximum concentration averages 15 minutes.

Indications

Memory, attention, other cognitive functions and emotional lability disorders (including in elderly patients) in:

the effects of brain injury,

post-communication syndrome,

Active ingredient

Composition

Active ingredient:

Omberacetam (noopept) – 10.0 mg;

excipients:

lactose monohydrate – 55.0 mg,

potato starch – 13.5 mg,

microcrystalline cellulose 101 – 21.2 mg,

/p>

magnesium stearate – 0.3 mg,

povidone (polyvinyl-pyrrolidone, povidone K-25) – 0.0008 mg.

How to take, the dosage

Interaction

Special Instructions

When increasing the dose of the drug is necessary (up to 30 mg/day), when using for a long time, as well as when using simultaneously with other drugs, when adverse reactions occur or when the condition worsens, consult a physician.

Influence on ability to drive, operate machinery

Contraindications

Side effects

Allergic reactions are possible.

In patients with arterial hypertension, mostly of a severe degree, against the background of taking the drug, a rise in blood pressure may be observed.

Overdose

Pregnancy use

The drug is contraindicated for use during pregnancy.