No-shpa forte, tablets 80 mg 24 pcs

Drotaverine is an isoquinoline derivative with chemical structure and pharmacological properties similar to papaverine, but with stronger and longer action. Drotaverine has a powerful antispasmodic effect on smooth muscles by inhibiting the phosphodiesterase enzyme (PDE). Phosphodiesterase enzyme is required for hydrolysis of cAMP (cyclic adenosine-3′, 5′-monophosphate) to AMP (adenosine-5′-monophosphate).

Indications

Auxiliary therapy:

Active ingredient

Composition

How to take, the dosage

Special Instructions

Contraindications

With caution

In case of arterial hypotension.

In pregnant women (see “Pregnancy and lactation”). Pregnancy and lactation

There is no evidence of teratogenic or embryotoxic effects or adverse effects on pregnancy based on limited retrospective data on the use of the drug in humans and data from animal studies when taking oral drotaverine. Despite this, caution should be exercised when using the drug in pregnant women and the drug should be prescribed only after careful weighing of the balance of benefits and risks to the mother and risks to the child.

There have been no studies on the excretion of drotaverine into maternal milk in animals. In the absence of such studies in animals and clinical data, it is not recommended to prescribe drotaverine during lactation.

Side effects

Overdose

In case of overdose, patients should be under medical supervision and, if necessary, they should be treated with symptomatic and supportive treatment for basic body functions.

There are no data on overdose of the drug.

Similarities