Neuromultivit, 60 pcs.

Neuromultivit – stimulates metabolism in the CNS, stimulates the regeneration of nervous tissue, analgesic.

Pharmacodynamics

Vitamin B1 as a result of phosphorylation processes is converted into cocarboxylase, which is a coenzyme of many enzymatic reactions. Vitamin B6 in phosphorylated form is a coenzyme in amino acid metabolism (decarboxylation, transamination, etc.), participates in the biosynthesis of many neurotransmitters (dopamine, noradrenaline, adrenaline, histamine, GABA). Vitamin B12 is necessary for normal hematopoiesis and maturation of red blood cells, is involved in the transfer of methyl groups (and other single-carbon fragments), the synthesis of nucleic acids, proteins, carbohydrates and lipids.

Indications

• polyneuropathy;
• neuritis; neuralgia; trigeminal neuralgia;
• Plexitis; intercostal neuralgia;
• Paresis of the facial nerve.

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Composition

One tablet contains:

Active ingredients: thiamine hydrochloride 100.00 mg; pyridoxine hydrochloride 200.00 mg; cyanocobalamin 0.20 mg.

Excipients: microcrystalline cellulose 80.0 mg, magnesium stearate 4.8 mg, povidone 15.0 mg.

The shell: macrogol 6000 9.0 mg, titanium dioxide 11.25 mg, talc 30.0 mg, hypromellose 7.5 mg, methyl methacrylate and ethyl acrylate copolymer 1 : 2 [30% dispersion] 2.25 mg.

How to take, the dosage

Prescribe orally 1 tablet. 1-3 times a day. Course duration is determined individually.

The tablets should be taken after a meal, without chewing and with a small amount of liquid.

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Interaction

When using Neuromultivit and levodopa concomitantly, a decrease in the antiparkinsonian efficacy of levodopa is noted.
When Neuromultivit and ethanol are used concomitantly the absorption of thiamine contained in the drug is sharply reduced (blood levels may decrease by 30%).
During the treatment with Neuromultivit it is not recommended to take multivitamin complexes that include B vitamins.

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Special Instructions

It is not recommended to use the drug in high doses for more than 4 weeks.

Contraindications

Hypersensitivity.

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Overdose

Symptoms: Clinical symptoms of overdose of the vitamins contained in Neuromultivit can only be expected after taking exceptionally high doses for a very long time.

Vitamin B1 – no overdose symptoms have been noted after oral administration.

Vitamin B6 – Neuropathies with ataxia and sensory disturbances, seizures with EEG changes and, in some cases, hypochromic anemia and seborrheic dermatitis have been described after taking more than 2 g/day.

Vitamin B12 – eczematous skin changes and acne have been observed after parenteral administration (in rare cases also after oral administration).

Treatment:conducting symptomatic therapy.

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Pregnancy use

It is not recommended to use Neuromultivit during pregnancy and lactation (breastfeeding) due to the lack of reliable clinical data confirming the safety of the drug during these periods.