Neurodiklovit, 30 pcs.

Pain, Pain in the neck, Radiculitis, Arthrosis, Tonsillitis, Neuralgia, Lumbago, Rheumatoid arthritis, Neuritis, Gout, Pain after injuries and operations, Adnexitis, Osteochondrosis, Periarthritis, Back pain, Sciatica, Joint pain (arthralgia), Pharyngitis, Arthritis, Osteoarthritis.ul>

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Indications

pain syndrome due to inflammation of non-rheumatic nature
inflammatory and degenerative diseases of the joints and spine (chronic polyarthritis, rheumatic and rheumatoid arthritis, ankylosing spondylitis, arthrosis, spondyloarthrosis)
neuritis and neuralgia (cervical syndrome, lumbago, sciatica)
acute gouty arthritis
rheumatic soft tissue damage.

Pharmacological effect

Neurodiclovit has an anti-inflammatory and analgesic effect.

Special instructions

Patients taking the drug must refrain from activities that require increased attention and rapid mental and motor reactions, and drinking alcohol.

Active ingredient

Diclofenac sodium, Thiamine, Pyridoxine, Cyanocobalamin

Composition

One capsule contains:

Active substances:

diclofenac sodium 50.0 mg;
mixture of vitamins: thiamine hydrochloride 50.0 mg; pyridoxine hydrochloride 50.0 mg;
cyanocobalamin 0.25 mg.

Excipients:

povidone K 25 8.42 mg,

methacrylic acid and ethyl acrylate copolymer (1: 1) dispersion 30% 5.60 mg,

triethyl citrate 0.60 mg, talc 3.08 mg.

Capsule shell: body:

titanium dioxide (E 171) 0.9240 mg,

red iron oxide dye (E 172) 0.0061 mg,

yellow iron oxide dye (E 172) 0.0924 mg,

gelatin 45.1775 mg.

Pregnancy

Neurodiclovit is not recommended for children under 18 years of age, pregnant women or during lactation.

Contraindications

individual intolerance to the components of Neurodiclovit, erosive and ulcerative lesions of the gastrointestinal tract in the acute phase
bleeding from the gastrointestinal tract
intracranial hemorrhages
hematopoietic disorders
hemostasis disorders (including hemophilia).

Side Effects

Allergic reactions, diarrhea, nausea, headache are possible.

Interaction

The drug increases plasma concentrations of digoxin, methotrexate, lithium and cyclosporine.

Reduces the effect of diuretics; against the background of potassium-sparing diuretics, the risk of hyperkalemia increases; against the background of anticoagulants, thrombolytic agents (alteplase, streptokinase, urokinase) – the risk of bleeding (usually from the gastrointestinal tract).

Reduces the effects of antihypertensive and hypnotic drugs.

Increases the likelihood of side effects of other NSAIDs and glucocorticosteroids (bleeding in the gastrointestinal tract), methotrexate toxicity and cyclosporine nephrotoxicity.

Acetylsalicylic acid reduces the concentration of diclofenac in the blood.

Concomitant use with paracetamol increases the risk of developing nephrotoxic effects of diclofenac.

Reduces the effect of hypoglycemic drugs.

Cefamandole, cefoperazone, cefotetan, valproic acid and plicamycin increase the incidence of hypoprothrombinemia.

Cyclosporine and gold preparations increase the effect of diclofenac on the synthesis of prostaglandins in the kidneys, which increases nephrotoxicity.

Concomitant use with ethanol, colchicine, corticotropin, serotonin reuptake inhibitors and St. John’s wort increases the risk of bleeding in the gastrointestinal tract.

Diclofenac enhances the effect of drugs that cause photosensitivity.

Antibacterial drugs from the quinolone group – the risk of developing seizures.

Drugs that block tubular secretion increase the plasma concentration of diclofenac, thereby increasing its toxicity.

The drug reduces the antiparkinsonian effectiveness of levodopa.

Ethanol sharply reduces the absorption of thiamine (blood levels can decrease by 30%). Long-term treatment with anticonvulsants can lead to thiamine deficiency. The use of colchicine and biguanides reduces the absorption of cyanocobalamin. While taking the drug, it is not recommended to take multivitamin complexes containing B vitamins.

Overdose

Symptoms: vomiting, bleeding from the gastrointestinal tract (GIT), epigastric pain, diarrhea, dizziness, tinnitus, lethargy, convulsions; rarely – increased blood pressure, acute renal failure, hepatotoxic effect, respiratory depression, coma.

Treatment: gastric lavage, activated charcoal, symptomatic therapy aimed at eliminating increased blood pressure, renal dysfunction, convulsions, gastrointestinal irritation, respiratory depression.

Forced diuresis and hemodialysis are ineffective (due to the significant connection with proteins and intensive metabolism).

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 ° C.

Keep out of the reach of children!

Shelf life

3 years.
Do not use after expiration date.

Manufacturer

G.L.Pharma GmbH, Austria