Nasol Advance, spray 0.025 mcg/dose 10 ml

Vasoconstrictor for local use in ENT practice.

Oxymetazoline hydrochloride causes vasoconstriction of mucous membranes of the nose, sinuses and Eustachian tube, which reduces their swelling and leads to relief of nasal breathing. Nasal breathing is relieved within 5-10 min after injection into the nasal cavity and lasts up to 12 hours.

Menthol, camphor, eucalyptol have local antiedematous, anti-inflammatory and antiseptic effect, liquefy thick mucus and improve its outflow from the paranasal sinuses and also contribute to increase the duration of action of the drug.

Indications

Active ingredient

Composition

1 vial contains:

Active substance:

oxymetazoline hydrochloride 0.025 mg;

Auxiliary substances:

benzalkonium chloride, 0.02 g;

camphor racemic, 0.17 g;

eucalyptol (cineol), 0.17 g;

levomenthol – 0.17 g;

dinatrium edetate dihydrate – 0.1 g;

polysorbate 80 – 0.2 g;

Propylene glycol – 10 g;

Sodium hydrophosphate dihydrate – 0.06 g;

Sodium dihydrophosphate dihydrate – 0.65 g;

Hydrochloric acid concentrated – 0.003 g;

Purified water – 89.711 g.

How to take, the dosage

Adults and children over 12 years of age are prescribed 2 to 3 injections into each nasal passage 2 times/day, children aged 6 to 12 years (under the supervision of an adult) – 1 injection into each nasal passage 2 times/day. Do not use the drug more than 2 times a day.

It is not recommended to use the drug for more than 3 days. If the drug is used frequently or for long periods of time, the feeling of difficulty in nasal breathing may reappear or worsen. If these symptoms occur, discontinue treatment and see a physician.

Do not tilt your head back and do not spray while lying down when injecting.

Interaction

In concomitant use with MAO inhibitors and tricyclic antidepressants, increased BP may be observed.

The drug slows absorption of local anesthetic drugs, prolonging their effect.

The co-administration of other vasoconstrictors increases the risk of side effects.

Special Instructions

It is not recommended to use Nasol Advans for more than 3 days.

Contact with the drug in the eyes should be avoided. The drug has an effect on vision, it may reduce reaction speed.

The drug should be used individually to avoid spreading infection.

Synopsis

Contraindications

– atrophic rhinitis;

– children under 6 years of age;

– pregnancy;

– lactation period;

– hypersensitivity to the drug components.

The drug should be used with caution in patients with cardiovascular diseases (arterial hypertension, CHD, chronic heart failure, tachycardia, arrhythmia), impaired carbohydrate metabolism (diabetes mellitus), disorders of thyroid function (hyperthyroidism), pheochromocytoma, prostatic hyperplasia with clinical symptoms, chronic renal insufficiency, closed-angle glaucoma, with concomitant use of MAO inhibitors, tricyclic antidepressants.

Side effects

Local reactions: sometimes a burning sensation or dry nasal membranes, dryness in the mouth and throat, sneezing, increased volume of nasal secretions.

In rare cases, after the effect of the drug passes, a strong feeling of “stuffy” nose (reactive hyperemia).

Systemic reactions: increased BP, headache, dizziness, palpitations, increased anxiety, nausea, insomnia.

In prolonged use of the drug (more than 7 days) reactive nasal mucosal hyperemia and nasal mucosal atrophy are possible.

Overdose

Symptoms: Prolonged or frequent application of the drug in the nasal cavity may cause nausea, increased BP, tachycardia, CNS depression.

Treatment:Symptomatic therapy is carried out.

Similarities