Motrin, tablets 250 mg 20 pcs

Migraine, Sore throat, Joint pain (arthralgia), Flu, Headache, Pain after injuries and operations, Arthritis, Back pain, Neck pain, Myalgia (muscle pain), Sciatica, Muscle pain (myalgia), Pain, Angina, Neuralgia (nerve pain), Menstrual pain (algodysmenorrhea), Osteoarthritis, Toothache, Infectious diseases, Lumbago, ArthrosisMild to moderate pain syndrome: Neuralgia, ossalgia, myalgia, lumbo-ischialgia, post-traumatic pain syndrome (sprains and contusions) accompanied by inflammation, postoperative pain (in trauma, orthopedics, gynecology, maxillofacial surgery), headache, migraine, algodysmenorrhea, adnexitis, toothache.

Symptomatic pain therapy in diseases of the musculoskeletal system, including bursitis, tendovaginitis.

In combination therapy of infectious and inflammatory diseases of the ear, throat and nose with a pronounced pain syndrome (pharyngitis, tonsillitis, otitis).

Feverish conditions with flu and colds.

The drug is used for symptomatic therapy (to reduce pain, inflammation and elevated body temperature) and has no effect on the progression of the main disease.

Active ingredient

Composition

How to take, the dosage

Interaction

When treating with anticoagulants, it should be borne in mind that naproxen may increase bleeding time. The drug should not be used simultaneously with other non-steroidal anti-inflammatory drugs (increased risk of side effects).

When concomitant use of guidantoin derivatives, anticoagulants or other drugs that bind significantly to plasma proteins, the effect of these drugs may be potentiated.

Naproxen may decrease the antihypertensive effects of propranololol and other beta-adrenoblockers, and may increase the risk of renal failure associated with the use of ACE inhibitors.

The effect of naproxen inhibits the natriuretic effect of furosemide.

Inhibition of renal clearance of lithium leads to increased plasma concentrations of lithium.

Probenecid administration increases plasma levels of naproxen.

Cyclosporine increases the risk of renal failure.

Naproxen slows the excretion of methotrexate, phenytoin, sulfonamides, increasing the risk of their toxic effects.

The antacids containing magnesium and aluminum decrease the absorption of naproxen.

Special Instructions

Do not exceed the doses given in the instructions. To reduce the risk of gastrointestinal adverse events, use the lowest effective dose for the shortest course possible. If pain and fever persist or get worse, you should see your doctor.

Patients with bronchial asthma, with blood clotting disorders, and patients with hypersensitivity to other analgesics should consult a physician before taking naproxen.

With caution, patients with liver disease and renal failure should be prescribed. In patients with renal insufficiency, creatinine clearance should be monitored. In chronic alcoholic and other forms of liver cirrhosis, the concentration of unbound naproxen is increased, so lower doses are recommended for these patients.

Naproxen should not be taken with other anti-inflammatory and pain medications unless prescribed by a physician. Lower doses are also recommended for elderly patients. Naproxen should be avoided for 48 hours before surgery. If 17 corticosteroids need to be determined, the drug should be discontinued 48 hours before the study. Similarly, naproxen may affect the determination of 5-hydroxyindoleacetic acid in urine. The use of naproxen, as well as other drugs that block the synthesis of prostaglandins, may affect fertility, so it is not recommended for women planning to become pregnant.

Synopsis

Contraindications

Side effects

Overdose

Significant overdose of the drug may be characterized by drowsiness, dyspeptic disorders (heartburn, nausea and vomiting, abdominal pain), weakness, tinnitus, irritability, in severe cases – bloody vomiting, melena, impaired consciousness, seizures and renal failure.

Treatment: gastric lavage, activated charcoal and symptomatic therapy: antacids, H2-histamine receptor blockers, proton pump inhibitors. Hemodialysis is ineffective.

Pregnancy use

Similarities