Mexiprim, 125 mg 30 pcs.
€6.09 €5.41
Mexiprim belongs to the heteroaromatic antioxidants.
It has a wide range of pharmacological activity: increases the body’s resistance to stress, exhibits anxiolytic effect, not accompanied by myorelaxant effect; has nootropic properties, prevents and reduces learning and memory disorders that occur with aging and exposure to various pathogenic factors; has anticonvulsant effect; exhibits antioxidant and antihypoxic properties; increases attention concentration and performance; weakens the toxic effects of alcohol.
The drug improves brain tissue metabolism and blood supply, improves microcirculation and blood rheology, reduces platelet aggregation.
Stabilizes membrane structures of blood cells (erythrocytes and platelets). It has hypolipidemic effect, decreases the total cholesterol and low-density lipoproteins.
The mechanism of action of Mexiprim is due to its antioxidant and membrane-protective effect.
It inhibits lipid peroxidation, increases superoxidase activity, increases lipid-protein ratio, decreases membrane viscosity and increases its fluidity.
Modulates the activity of membrane-bound enzymes (calcium-independent phosphodiesterase, adenylate cyclase, acetylcholinesterase), receptor complexes (benzodiazepine, GABA, acetylcholine) that increases their ability to bind to ligands, maintains structural and functional organization of biomembranes, neurotransport and improves synaptic transmission.
Mexiprim increases dopamine content in the brain.
Causes compensatory activation of aerobic glycolysis and a decrease in the degree of inhibition of oxidative processes in the Krebs cycle in hypoxia with an increase in ATP and creatine phosphate, activation of energy-synthesizing functions of mitochondria, stabilization of cell membranes.
Indications
Attention and memory disorders, Headache, Anxiety, Weakness and fatigue, Dizziness, Angina
- anxiety disorders in neurotic and neurosis-like states;
- vascular dystonia;
- .Mild cognitive disorders of different genesis (with psychoorganic syndrome and asthenic disorders due to acute and chronic cerebral circulation disorders, craniocerebral injuries, neuroinfections and intoxications, senile and atrophic processes);
- memory disorders and intellectual disability in the elderly
- exposure to extreme (stress) factors;
- alcohol withdrawal syndrome with a predominance of neurosis-like and autonomic-vascular disorders.
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Active ingredient
Ethylmethylhydroxypyridine succinate
Composition
1 tablet contains:
The active ingredient – ethylmethylhydroxypyridine succinate in terms of 100% substance – 0.125 g.
Auxiliary substances (tablet core):
Kaolin – 0.00247 g,
Carboxymethyl starch sodium – 0.01258 g,
Microcrystalline cellulose – 0,1135 g,
Povidone – 0,0134 g,
Talc – 0,0053 g,
Calcium stearate – 0,00275 g.
Auxiliary substances (coating):
Hypromellose – 0.00495 g,
Macrogol – 0.00128 g,
Titanium dioxide – 0.00165 g,
Talc – 0.00037 g.
How to take, the dosage
Mexicaprim is administered orally.
Therapeutic doses used and duration of treatment are determined by the sensitivity of patients to the drug.
The treatment starts with a dose of 0.25-0.5 g; the average daily dose is 0.25-0.5 g, the maximum daily dose is 0.8 g. The daily dose of the drug is divided into 2-3 doses during the day.
To treat patients with anxiety disorders, autonomic-vascular dysfunctions and cognitive disorders Mexiprim is used for 2-6 weeks.
In relieving alcohol withdrawal syndrome Mexiprim is used for 5-7 days.
Course therapy with Mexiprim is completed gradually, reducing the dose of the drug over 2-3 days.
Interaction
Compatible with psychotropic drugs.
It enhances the effect of benzodiazepine anxiolytics, anticonvulsants (carbamazepine), anti-Parkinsonian drugs (levodopa), reduces the toxic effects of ethyl alcohol.
Special Instructions
The degree of restriction is determined by individual tolerance of the drug. During treatment, caution should be exercised when driving motor transport and engaging in other potentially dangerous activities that require high concentration and quick psychomotor reactions.
Synopsis
Tablets are round, biconvex, film-coated, white to white with a creamy tint, on the break – white to white with a grayish or yellowish or creamy tint.
Contraindications
- Excessive individual sensitivity to Mexiprim
- acute hepatic and renal dysfunction
- childhood
- pregnancy
- Breastfeeding.
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Side effects
Individual adverse reactions are possible: nausea and dry mouth, drowsiness, allergic reactions.
Overdose
Symptoms: sleep disturbance (insomnia, in some cases drowsiness).
Treatment: as a rule, it is not required – symptoms disappear on their own within a day. In severe cases of insomnia, it is recommended to take nitrazepam 10 mg, oxazepam 10 mg or diazepam 5 mg.
Pregnancy use
The possibility and safety of using Mexiprim in pregnancy and lactation is currently insufficiently studied, so the use of the drug in this category of patients is contraindicated.
Similarities
Mexidol, Mexifin, Neurox, Medomexi, Mexicor, Evrin, MetucinVel, Neuromexol
Weight | 0.020 kg |
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Shelf life | 5 years. Do not use after the expiry date stated on the package. |
Conditions of storage | In a dry place, protected from light and out of the reach of children, at a temperature not exceeding 30 ° C. |
Manufacturer | Obninsk HFC, Russia |
Medication form | pills |
Brand | Obninsk HFC |
Other forms…
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