Melarithm, 3 mg 24 pcs

It is a synthetic analogue of the pineal gland hormone (epiphysis). It normalizes circadian rhythms. It regulates sleep-wake cycle, daily changes of locomotor activity and body temperature.

It helps to normalize night sleep (accelerates falling asleep, improves the quality of sleep, reduces the number of night awakenings, improves well-being upon awakening without a feeling of dullness, weariness and tiredness upon awakening; dreams become more vivid and emotionally rich).

The body adapts to rapid changes in time zones, reduces stress reactions.

It has immune-stimulating and strong antioxidant properties.

Inhibits secretion of gonadotropins and, to a lesser extent, other adenohypophysis hormones: corticotropin, thyrotropin and somatotropin.

It is not addictive or dependent.

Pharmacokinetics

In oral administration, it is quickly and completely adsorbed and easily passes the histohematic barriers, including the blood-brain barrier. It has a short half-life.

Indications

As a sleeping pill.

As an adaptogen to normalize biological rhythms.

Pharmacological effect

It is a synthetic analogue of the pineal gland hormone (epiphysis). Normalizes circadian rhythms. Regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature.

Helps normalize night sleep (accelerates falling asleep, improves sleep quality, reduces the number of night awakenings, improves well-being after waking up in the morning, does not cause a feeling of lethargy, weakness and fatigue upon awakening, dreams become more vivid and emotionally rich).

Adapts the body to rapid changes in time zones, reduces stress reactions.

Shows immunostimulating and pronounced antioxidant properties.

Inhibits the secretion of gonadotropins, and to a lesser extent, other hormones of the adenohypophysis – corticotropin, thyrotropin and somatotropin.

Does not cause addiction or dependence.

Pharmacokinetics

When taken orally, it is quickly and completely adsorbed and easily passes histohematic barriers, including the blood-brain barrier. Has a short half-life.

Special instructions

During the period of use of the drug, it is recommended to avoid exposure to bright light.

It is necessary to inform women who want to become pregnant that the drug has a weak contraceptive effect.

Impact on the ability to drive vehicles and machinery

During the treatment period, it is necessary to refrain from driving vehicles and engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Active ingredient

Melatonin

Composition

Melatonin – 3 mg.

Excipients:

microcrystalline cellulose – 82.4 mg,

croscarmellose sodium (sodium starch glycolate) – 10.5 mg,

calcium hydrogen phosphate dihydrate – 82.4 mg,

mannitol – 44 mg,

macrogol 6000 (polyethylene glycol 6000) – 15 mg,

magnesium stearate – 2.7 mg.

Shell composition:

opadry II (polyvinyl alcohol – 2.4 mg, titanium dioxide – 1.5 mg, macrogol – 1.212 mg, talc – 0.888 mg).

Contraindications

Hypersensitivity, severe renal dysfunction, autoimmune diseases, leukemia, lymphoma, allergic reactions, lymphogranulomatosis, myeloma, epilepsy, diabetes mellitus, chronic renal failure, pregnancy and breastfeeding.

Side Effects

From the immune system: allergic reactions.

From the central nervous system: headache, morning drowsiness.

From the digestive system: nausea, vomiting, diarrhea.

Other: swelling in the first week of use.

Interaction

Melatonin enhances the effect of drugs that depress the central nervous system and beta-blockers.

It is not recommended to take melatonin together with hormonal medications.

Melatonin is incompatible with monoamine oxidase inhibitors (MAOIs), glucocorticosteroids and cyclosporine.

Overdose

Symptoms. Increased severity of side effects.

Treatment. Gastric lavage, symptomatic therapy.

Storage conditions

The drug should be stored in a dry place, protected from light and out of reach of children, at a temperature not exceeding 25°C.

Shelf life

2 years.

Manufacturer

Alium JSC, Russia